ID   SARA_STRGC              Reviewed;         663 AA.
AC   P31306; A8AYX4;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Oligopeptide-binding protein SarA;
DE   AltName: Full=76 kDa cell surface lipoprotein;
DE   Flags: Precursor;
GN   Name=sarA; Synonyms=hppA; OrderedLocusNames=SGO_1712;
OS   Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 /
OS   DL1 / V288).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=467705;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288;
RX   PubMed=17720781; DOI=10.1128/jb.01023-07;
RA   Vickerman M.M., Iobst S., Jesionowski A.M., Gill S.R.;
RT   "Genome-wide transcriptional changes in Streptococcus gordonii in response
RT   to competence signaling peptide.";
RL   J. Bacteriol. 189:7799-7807(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-55, DIACYLGLYCEROL AT CYS-23, AND
RP   PALMITOYLATION AT CYS-23.
RX   PubMed=1339408; DOI=10.1128/iai.60.3.1225-1228.1992;
RA   Jenkinson H.F.;
RT   "Adherence, coaggregation, and hydrophobicity of Streptococcus gordonii
RT   associated with expression of cell surface lipoproteins.";
RL   Infect. Immun. 60:1225-1228(1992).
CC   -!- FUNCTION: May be involved in the expression of cell surface properties
CC       important for colonization of the human oral cavity. It may also be
CC       involved in uptake processes.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000725; ABV10882.1; -; Genomic_DNA.
DR   EMBL; S85398; AAB21606.1; -; Genomic_DNA.
DR   PIR; A43896; A43896.
DR   RefSeq; WP_012130757.1; NC_009785.1.
DR   AlphaFoldDB; P31306; -.
DR   SMR; P31306; -.
DR   STRING; 467705.SGO_1712; -.
DR   EnsemblBacteria; ABV10882; ABV10882; SGO_1712.
DR   KEGG; sgo:SGO_1712; -.
DR   eggNOG; COG4166; Bacteria.
DR   HOGENOM; CLU_026497_0_0_9; -.
DR   OMA; HFINNGA; -.
DR   Proteomes; UP000001131; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR023765; SBP_5_CS.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS01040; SBP_BACTERIAL_5; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Peptide transport;
KW   Protein transport; Reference proteome; Signal; Transport.
FT   SIGNAL          1..22
FT   CHAIN           23..663
FT                   /note="Oligopeptide-binding protein SarA"
FT                   /id="PRO_0000018189"
FT   REGION          637..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303,
FT                   ECO:0000269|PubMed:1339408"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305|PubMed:1339408"
SQ   SEQUENCE   663 AA;  73371 MW;  EBCEAC3F7077BEE3 CRC64;
     MKKGKILALA GVALLATGVL AACSNSTSNS SNSSSSGADQ VFNYIYEVDP ENLNYLISSK
     AATTDLTANL IDGLLENDNY GNLVPSMAED WTVSKDGLTY TYTLRKDAKW YTSDGEEYAD
     VKAQDFVAGL KYAADNKSET LYLVQSSIKG LDDYVNGKTK DFSSVGVKAV DDHTVQYTLN
     EPESFWNSKT TMGILYPVNE EFLKSKGDKF AQSADPTSLL YNGPFLLKSI TSKSSIEFAK
     NPNYWDKDNV HVSDVKLTYF DGQDQGKPAE QFAKGALSAA RLAPTSATFS KVEKEFKDNI
     VYTPQDSTSY LVGVNIDRQA YNHTAKSSDA QKSSTKKALM NKDFRQALSF AFDRTAYASQ
     VNGKEGATKM LRNLYIPPTF VQADGKSFGE LVKEKVASYG DEWKDVNFDD AQDGLYNKEK
     AKAEFAKAKK ALQEEGVEFP IHLDMPVDQT ATAKVQRVQS LKQSIESSLG TDNVVVDIHQ
     MKTDDVLNIT YYAASAAEED WDISDNVGWS PDYQDPSTYL EIIKPGGENT KTFLGFDGKE
     NAAAEQVGLK EYAKLVDEAA AEKTDVNKRY EKYATAQAWL TDSALLIPTT SRTGRPVLTK
     IVPFTAPFAW SGAKGRDMAS YKYLKLQDKA VTAKEYQKAQ EKWNKERAES NKKAQEELEK
     HVK