SARG_BOVIN
ID SARG_BOVIN Reviewed; 597 AA.
AC A5D7K1;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Specifically androgen-regulated gene protein;
GN Name=SARG;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal skin;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative androgen-specific receptor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SARG family. {ECO:0000305}.
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DR EMBL; BC140587; AAI40588.1; -; mRNA.
DR RefSeq; NP_001091934.1; NM_001098464.1.
DR AlphaFoldDB; A5D7K1; -.
DR SMR; A5D7K1; -.
DR STRING; 9913.ENSBTAP00000024149; -.
DR PaxDb; A5D7K1; -.
DR PeptideAtlas; A5D7K1; -.
DR Ensembl; ENSBTAT00000024149; ENSBTAP00000024149; ENSBTAG00000018143.
DR GeneID; 539441; -.
DR KEGG; bta:539441; -.
DR CTD; 539441; -.
DR VEuPathDB; HostDB:ENSBTAG00000018143; -.
DR VGNC; VGNC:52641; C16H1orf116.
DR eggNOG; ENOG502RGW5; Eukaryota.
DR GeneTree; ENSGT00390000017874; -.
DR HOGENOM; CLU_035136_0_0_1; -.
DR InParanoid; A5D7K1; -.
DR OMA; NSHTPGE; -.
DR OrthoDB; 484727at2759; -.
DR TreeFam; TF336615; -.
DR Proteomes; UP000009136; Chromosome 16.
DR Bgee; ENSBTAG00000018143; Expressed in esophagus and 65 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR InterPro; IPR026152; SARG.
DR PANTHER; PTHR21555; PTHR21555; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Phosphoprotein; Receptor; Reference proteome.
FT CHAIN 1..597
FT /note="Specifically androgen-regulated gene protein"
FT /id="PRO_0000318574"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 130
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BW04"
FT MOD_RES 132
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BW04"
FT MOD_RES 515
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BW04"
SQ SEQUENCE 597 AA; 63052 MW; 40BB3747CECD60AE CRC64;
MPERELWPAG PGLEPATRVG SCDSMMSTTS TRSGSSDSSY DFLSAEEKEC LLFLEETIGS
LDTEADSGLS TEKSEQATTP QVPRALPKTQ PAPQGHPEEI TGRVPEPKRV TPFSSAHPPG
PQSLGLRSGS YSLPRNIHIG RNQNLRKSTT LTNSHNPGGS EGLVSGPETE QVSQSREPRQ
TLATPPDAAL ELDGALIPPP EAFRDTQPQQ RGQGSLPRGP GELSPRPQVH PSLSSQRNRE
PAPEAMSQKA SEKGSTGEPV PPRPPPLVSS RDAGSGDAAV LSGGHPSARP APLTAPKPRK
LPPNIVLKSS RSSFHSDPQN RLSRHSEAAP GDPSPASSSL QEQRKARREA LEKLGLPQDQ
EEPSPRLSRP SVRLKETGVQ AVSPAPAQVP GRAPAAAPTQ GPSPGKAPAL AQPPSPGKVL
VPAQESTPGT APAAKSTPIP IPKGPRAHSP LTQRKPDSGL TLQESGVPGL RQMSFKSNTL
ERSGIGLSSY LSAEKASSPQ TSTSLEKGSF LDRISPSVLR NSRPRPASLG TGKDFEGIQV
GKLADLEQEG GPKRLSFQGQ SRDKLPRPPC VSVRISPKGV SDEHRREALK KLGLLKE