ID   SARV_STAAN              Reviewed;         116 AA.
AC   Q7A442;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=HTH-type transcriptional regulator SarV;
DE   AltName: Full=Staphylococcal accessory regulator V;
GN   Name=sarV; OrderedLocusNames=SA2062;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- FUNCTION: Part of the pathway by which MgrA and SarA control autolysis.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SarA family. {ECO:0000305}.
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DR   EMBL; BA000018; BAB43359.1; -; Genomic_DNA.
DR   PIR; F90024; F90024.
DR   RefSeq; WP_000066900.1; NC_002745.2.
DR   AlphaFoldDB; Q7A442; -.
DR   SMR; Q7A442; -.
DR   EnsemblBacteria; BAB43359; BAB43359; BAB43359.
DR   KEGG; sau:SA2062; -.
DR   HOGENOM; CLU_2095367_0_0_9; -.
DR   OMA; QVFYFFN; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR010166; SarA/Rot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR01889; Staph_reg_Sar; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Transcription; Transcription regulation;
KW   Virulence.
FT   CHAIN           1..116
FT                   /note="HTH-type transcriptional regulator SarV"
FT                   /id="PRO_0000219608"
FT   DNA_BIND        51..74
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   116 AA;  13986 MW;  CE7ACED821E33EF9 CRC64;
     MSNKVQRFIE AERELSQLKH WLKTTHKISI EEFVVLFKVY EAEKISGKEL RDTLHFEMLW
     DTSKIDVIIR KIYKKELISK LRSETDERQV FYFYSTSQKK LLDKITKEIE VLSVTN