ID   SARZ_STAES              Reviewed;         148 AA.
AC   Q8CN77;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=HTH-type transcriptional regulator SarZ;
DE   AltName: Full=Staphylococcal accessory regulator Z;
GN   Name=sarZ; OrderedLocusNames=SE_1967;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SarZ family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05608.1; -; Genomic_DNA.
DR   RefSeq; NP_765522.1; NC_004461.1.
DR   RefSeq; WP_002438330.1; NZ_WBME01000017.1.
DR   AlphaFoldDB; Q8CN77; -.
DR   SMR; Q8CN77; -.
DR   STRING; 176280.SE_1967; -.
DR   EnsemblBacteria; AAO05608; AAO05608; SE_1967.
DR   GeneID; 50017939; -.
DR   KEGG; sep:SE_1967; -.
DR   PATRIC; fig|176280.10.peg.1920; -.
DR   eggNOG; COG1846; Bacteria.
DR   HOGENOM; CLU_083287_3_2_9; -.
DR   OMA; VERCFLP; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..148
FT                   /note="HTH-type transcriptional regulator SarZ"
FT                   /id="PRO_0000284463"
FT   DOMAIN          9..139
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   DNA_BIND        55..78
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
SQ   SEQUENCE   148 AA;  17491 MW;  F3C407CF70C4C745 CRC64;
     MYVENSYLSK QLCFLFYVSS KEIIKKYTDY LKEYGLTYTG YIVLMAIEDD EKLNIKKLGE
     RVFLDSGTLT PLLKKLEKKN YVIRTREEQD ERNLQISLTE RGKDIQNVLS DISQSVFNEF
     NITQEETQNL VEDLQNFVTK NFDKTVEK