ID   SARZ_STAHJ              Reviewed;         147 AA.
AC   Q4L8Q3;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=HTH-type transcriptional regulator SarZ;
DE   AltName: Full=Staphylococcal accessory regulator Z;
GN   Name=sarZ; OrderedLocusNames=SH0663;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SarZ family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE03972.1; -; Genomic_DNA.
DR   RefSeq; WP_011274988.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8Q3; -.
DR   SMR; Q4L8Q3; -.
DR   STRING; 279808.SH0663; -.
DR   EnsemblBacteria; BAE03972; BAE03972; SH0663.
DR   GeneID; 58063146; -.
DR   KEGG; sha:SH0663; -.
DR   eggNOG; COG1846; Bacteria.
DR   HOGENOM; CLU_083287_3_2_9; -.
DR   OMA; MMVLWER; -.
DR   OrthoDB; 1626703at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..147
FT                   /note="HTH-type transcriptional regulator SarZ"
FT                   /id="PRO_0000284465"
FT   DOMAIN          9..139
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   DNA_BIND        55..78
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
SQ   SEQUENCE   147 AA;  17317 MW;  95D1C8B3F8DB29BF CRC64;
     MYIKDSYLSN QLCFLLYVTS KEVIKKYTYY LKKHDLTYTS FMVIMAIENE EKINIKSLGR
     RVFLDSGTLT PLLKKLEKKG YVQRMREKED ERNLQITLTE SGINIKPTLK AISDQVFEDF
     DISQDEKDNL VNSLKHVISN NFDYTTH