ID   SARZ_STAS1              Reviewed;         146 AA.
AC   Q49ZX3;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=HTH-type transcriptional regulator SarZ;
DE   AltName: Full=Staphylococcal accessory regulator Z;
GN   Name=sarZ; OrderedLocusNames=SSP0505;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS   20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41;
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA   Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SarZ family. {ECO:0000305}.
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DR   EMBL; AP008934; BAE17650.1; -; Genomic_DNA.
DR   RefSeq; WP_011302461.1; NZ_MTGA01000036.1.
DR   AlphaFoldDB; Q49ZX3; -.
DR   SMR; Q49ZX3; -.
DR   STRING; 342451.SSP0505; -.
DR   PRIDE; Q49ZX3; -.
DR   EnsemblBacteria; BAE17650; BAE17650; SSP0505.
DR   KEGG; ssp:SSP0505; -.
DR   PATRIC; fig|342451.11.peg.509; -.
DR   eggNOG; COG1846; Bacteria.
DR   HOGENOM; CLU_083287_3_2_9; -.
DR   OMA; MMVLWER; -.
DR   OrthoDB; 1626703at2; -.
DR   Proteomes; UP000006371; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..146
FT                   /note="HTH-type transcriptional regulator SarZ"
FT                   /id="PRO_0000284466"
FT   DOMAIN          9..139
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   DNA_BIND        55..78
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
SQ   SEQUENCE   146 AA;  17036 MW;  5AAE4D7AD5AFACB2 CRC64;
     MEEKDNTLER QLCFLFYVSS KEIIKKYTSY LKEFDLTYTG YIVLLAIGVE EKLNIKTLGA
     RVFLDSGTLT PLLKKLEKKG YVTRTREIDD ERNLQIALTT KGKDIKEPLS NISKQVFNEF
     DMEVDEAIDL KETLQNFVNK HFQQNI