位置:首页 > 蛋白库 > SASA_PROM0
SASA_PROM0
ID   SASA_PROM0              Reviewed;         372 AA.
AC   A3PDI2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Adaptive-response sensory-kinase SasA {ECO:0000255|HAMAP-Rule:MF_01837};
DE            EC=2.7.-.- {ECO:0000255|HAMAP-Rule:MF_01837};
DE   AltName: Full=Synechococcus adaptive sensor protein A {ECO:0000255|HAMAP-Rule:MF_01837};
GN   Name=sasA {ECO:0000255|HAMAP-Rule:MF_01837}; OrderedLocusNames=P9301_11841;
OS   Prochlorococcus marinus (strain MIT 9301).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9301;
RX   PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA   Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA   Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA   Richardson P., Chisholm S.W.;
RT   "Patterns and implications of gene gain and loss in the evolution of
RT   Prochlorococcus.";
RL   PLoS Genet. 3:2515-2528(2007).
CC   -!- FUNCTION: May be involved in signal transduction. Participates in the
CC       KaiABC clock protein complex, which constitutes the main circadian
CC       regulator in cyanobacteria, via its interaction with KaiC. Required for
CC       robustness of the circadian rhythm of gene expression and is involved
CC       in clock outputs. {ECO:0000255|HAMAP-Rule:MF_01837}.
CC   -!- SUBUNIT: Interacts with KaiC. Participates in the KaiABC complex, whose
CC       core is composed of a KaiC homohexamer, a KaiB dimer and two KaiA
CC       dimers. {ECO:0000255|HAMAP-Rule:MF_01837}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000576; ABO17807.1; -; Genomic_DNA.
DR   RefSeq; WP_011863135.1; NC_009091.1.
DR   AlphaFoldDB; A3PDI2; -.
DR   SMR; A3PDI2; -.
DR   STRING; 167546.P9301_11841; -.
DR   EnsemblBacteria; ABO17807; ABO17807; P9301_11841.
DR   KEGG; pmg:P9301_11841; -.
DR   eggNOG; COG2205; Bacteria.
DR   HOGENOM; CLU_723030_0_0_3; -.
DR   OMA; AHYGQIW; -.
DR   Proteomes; UP000001430; Chromosome.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   HAMAP; MF_01837; Kinase_SasA; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR011649; KaiB_domain.
DR   InterPro; IPR023527; Kinase_SasA.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF07689; KaiB; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM01248; KaiB; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   3: Inferred from homology;
KW   Biological rhythms; Kinase; Phosphoprotein; Reference proteome;
KW   Transferase; Two-component regulatory system.
FT   CHAIN           1..372
FT                   /note="Adaptive-response sensory-kinase SasA"
FT                   /id="PRO_1000088441"
FT   DOMAIN          147..360
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01837"
FT   MOD_RES         150
FT                   /note="Phosphohistidine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01837"
SQ   SEQUENCE   372 AA;  42438 MW;  240A90FCA860CE2E CRC64;
     MNDKKELKLI LVAARNQLSS NDIKSLIAYL ESDDCEFEIS LQISEPTEQP ELLELHRLVA
     IPALIKVSPA PKQIFAGSNI FSQLQKWLPR WTQEGLTKNL GINLQPSKID SIRTQKEFLL
     EDELLVLRQE NETLTKRIES QERLLRMVAH ELRTPLTAAT LAVQSQKLGQ IDISKLQEVI
     KRRLEEIELL SQDLLEVGTT KWEALFNPQK IDLGNISAEV ILELEKFWRL RNIEIDTDIP
     SDLPSVFADQ RRMRQVFLNL IENAIKFSRD SGSIKITMIH KTNQWVEITI CDKGAGIPLS
     EQKRIFLDRV RLPQTSEGTS GFGIGLSVCR RIVQVHGGRI WVVSEVGVGS CFHFTVPVWQ
     GQNKEQQYLT KG
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024