ID   SAT20_STACB             Reviewed;         712 AA.
AC   A0A084AFG9;
DT   22-NOV-2017, integrated into UniProtKB/Swiss-Prot.
DT   29-OCT-2014, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Satratoxin biosynthesis SC3 cluster transcription factor SAT20 {ECO:0000303|PubMed:25015739};
DE   AltName: Full=Satratoxin biosynthesis SC3 cluster protein 20 {ECO:0000303|PubMed:25015739};
GN   Name=SAT20 {ECO:0000303|PubMed:25015739}; ORFNames=S7711_07410;
OS   Stachybotrys chartarum (strain CBS 109288 / IBT 7711) (Toxic black mold)
OS   (Stilbospora chartarum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Stachybotryaceae; Stachybotrys.
OX   NCBI_TaxID=1280523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION, AND
RP   FUNCTION.
RC   STRAIN=CBS 109288 / IBT 7711;
RX   PubMed=25015739; DOI=10.1186/1471-2164-15-590;
RA   Semeiks J., Borek D., Otwinowski Z., Grishin N.V.;
RT   "Comparative genome sequencing reveals chemotype-specific gene clusters in
RT   the toxigenic black mold Stachybotrys.";
RL   BMC Genomics 15:590-590(2014).
CC   -!- FUNCTION: Transcriptional regulator that may regulate the expression of
CC       the satratoxin biosynthesis SC3 cluster, one of the 3 clusters involved
CC       in the biosynthesis of satratoxins, trichothecene mycotoxins that are
CC       associated with human food poisonings (PubMed:25015739).
CC       {ECO:0000305|PubMed:25015739}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- MISCELLANEOUS: Trichothecenes are sesquiterpenoid toxins that act by
CC       inhibiting protein biosynthesis. {ECO:0000305}.
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DR   EMBL; KL648755; KEY64048.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A084AFG9; -.
DR   EnsemblFungi; KEY64048; KEY64048; S7711_07410.
DR   HOGENOM; CLU_387879_0_0_1; -.
DR   OrthoDB; 709739at2759; -.
DR   Proteomes; UP000028045; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   SUPFAM; SSF57701; SSF57701; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA-binding; Metal-binding; Nucleus; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..712
FT                   /note="Satratoxin biosynthesis SC3 cluster transcription
FT                   factor SAT20"
FT                   /id="PRO_0000442409"
FT   DNA_BIND        306..339
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          530..560
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..283
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   712 AA;  80033 MW;  909FA8FE28317451 CRC64;
     MPNLPGSSDS TQRHQRNPGT DELVCSSTKP NAAQENADTE LAQEKHPQLL SPQTDIPPVC
     SQPNVSFAQC WDQNFFLDAA LTGQNSMTLL GVFDLPNSHM NLTETLSSQL GLEPSQNAFG
     QGSFDPFVPS SEPSVHSTDN PWPSLPTQLA FQPTNNNTSS LALLGPDPEQ LSTLPSSWTG
     PLDEWPPLDL GQDFAALLSP TYQAFEATPR HTHAHAHQPP RATRHITSQQ SPEPYVQVHS
     TAKIVDRFLV PIAPKPILVE RDGPVSGASL PSNPPTALSS TGTRKRKRFN KADRERVNQM
     RKLGSCFRCR MYKENCDPGL PCKNCMRVQV TRRTFFGPCI RIKWEEVHTF RAGDGDLGQI
     RATLQTFQWT LGGQVKSIDV QWPFRDDKVK PPILSIECQQ FLPKHEHVAE EYSVAGQAYK
     ILLPPWACSN TKAASKKVEA FVRQCQAPLE EEIRHTLNDP ILLLTLDEAR RYRNETGSKL
     VATALEIYAG AMMNSRYPAS TESDIFGVVD QLHTPYFFDK VPLPPQLTCQ IQIMVAQVML
     DKQKNALKRL QERALSKNRH KVWYECYLTI FILLATIELV YQVQLRFVKA KQGVSDRNAT
     NLSYVTQYMI EEWEESILTL VGLFHCVMNG GLPFTQSWED GGENHRLTEL DDKALVYVRS
     LKAEIEQRRG ELIALRNRRG RWRYEQPLAA ICQLFLPSQD GDKGEGRAAP PS