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SAT2_ORYSJ
ID   SAT2_ORYSJ              Reviewed;         354 AA.
AC   Q10S58; A0A0P0VSQ5; Q10S57; Q8H8D0;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Probable serine acetyltransferase 2;
DE            EC=2.3.1.30;
DE   AltName: Full=OsSERAT3;1;
GN   Name=SAT2; OrderedLocusNames=Os03g0133900, LOC_Os03g04140;
GN   ORFNames=OJ1006F06.16;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 1/2.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q10S58-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q10S58-2; Sequence=VSP_036319, VSP_036320;
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN05506.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC099399; AAN05506.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF93836.1; -; Genomic_DNA.
DR   EMBL; DP000009; ABF93837.1; -; Genomic_DNA.
DR   EMBL; AP008209; BAF10793.1; -; Genomic_DNA.
DR   EMBL; AP014959; BAS82165.1; -; Genomic_DNA.
DR   EMBL; AK067089; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015630173.1; XM_015774687.1. [Q10S58-1]
DR   AlphaFoldDB; Q10S58; -.
DR   SMR; Q10S58; -.
DR   STRING; 4530.OS03T0133900-01; -.
DR   PaxDb; Q10S58; -.
DR   PRIDE; Q10S58; -.
DR   EnsemblPlants; Os03t0133900-01; Os03t0133900-01; Os03g0133900. [Q10S58-1]
DR   GeneID; 4331528; -.
DR   Gramene; Os03t0133900-01; Os03t0133900-01; Os03g0133900. [Q10S58-1]
DR   KEGG; osa:4331528; -.
DR   eggNOG; KOG4750; Eukaryota.
DR   HOGENOM; CLU_051638_0_0_1; -.
DR   InParanoid; Q10S58; -.
DR   OMA; HSIRLDI; -.
DR   OrthoDB; 1337060at2759; -.
DR   PlantReactome; R-OSA-1119331; Cysteine biosynthesis I.
DR   UniPathway; UPA00136; UER00199.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q10S58; OS.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd03354; LbH_SAT; 1.
DR   Gene3D; 1.10.3130.10; -; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR010493; Ser_AcTrfase_N.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF06426; SATase_N; 1.
DR   SMART; SM00971; SATase_N; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR01172; cysE; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Alternative splicing; Amino-acid biosynthesis;
KW   Reference proteome; Transferase.
FT   CHAIN           1..354
FT                   /note="Probable serine acetyltransferase 2"
FT                   /id="PRO_0000363659"
FT   VAR_SEQ         305..326
FT                   /note="SMAVGNPAKVVGYKDKEDPSLT -> REQNQGRRAGRGGRGDNMIMIK (in
FT                   isoform 2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_036319"
FT   VAR_SEQ         327..354
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_036320"
FT   CONFLICT        347
FT                   /note="K -> R (in Ref. 5; AK067089)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   354 AA;  37517 MW;  64C4029A13CE6FB5 CRC64;
     MTSCGCLVLE KVEDHGGEAA GRGRGRLAQG GGGGGGGCGS CAGEWRSRSE TMFPIYVMGS
     SRASSAAAAR GIVDAAGDPI WEAVKSEAKS EAEKEPILSS FLYASVLSHD CLERALSFVL
     ANRLEDPTLL ATQLIDIFND VMMNNKDIRR SIRLDAQAFK DRDPACAQYS WALLYLKGYH
     SVQSYRIAHV LWNQGRKVLA LALQSRISEV FAVDIHPAAR IGEGILLDHG TGLVIGETAI
     VGNWVSLMQG VTLGGTGKEN GDRHPKIGQG ALLGAGATIL GNINVGEGAM IAAGSLVLKD
     VPPHSMAVGN PAKVVGYKDK EDPSLTMKHD ARRDYFEHVA VSFSDDKANG SVVK
 
 
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