SAT_RIFPS
ID SAT_RIFPS Reviewed; 437 AA.
AC Q54506;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Sulfate adenylyltransferase;
DE EC=2.7.7.4;
DE AltName: Full=ATP-sulfurylase;
DE AltName: Full=Sulfate adenylate transferase;
DE Short=SAT;
GN Name=sat; Synonyms=sopT;
OS Riftia pachyptila sulfur-oxidizing endosymbiont.
OC Bacteria.
OX NCBI_TaxID=35843;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8206850; DOI=10.1128/jb.176.12.3723-3729.1994;
RA Laue B., Nelson D.C.;
RT "Characterization of the gene encoding the autotrophic ATP sulfurylase from
RT the bacterial endosymbiont of the hydrothermal vent tubeworm Riftia
RT pachyptila.";
RL J. Bacteriol. 176:3723-3729(1994).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H(+) + sulfate = adenosine 5'-phosphosulfate +
CC diphosphate; Xref=Rhea:RHEA:18133, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:58243; EC=2.7.7.4;
CC -!- PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from
CC sulfate: step 1/3.
CC -!- SIMILARITY: Belongs to the sulfate adenylyltransferase family.
CC {ECO:0000305}.
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DR EMBL; L26897; AAA72419.1; -; Genomic_DNA.
DR PDB; 1JHD; X-ray; 1.70 A; A=1-386.
DR PDBsum; 1JHD; -.
DR AlphaFoldDB; Q54506; -.
DR SMR; Q54506; -.
DR BioCyc; MetaCyc:MON-12450; -.
DR UniPathway; UPA00140; UER00204.
DR EvolutionaryTrace; Q54506; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0070814; P:hydrogen sulfide biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.620; -; 1.
DR HAMAP; MF_00066; Sulf_adenylyltr; 1.
DR InterPro; IPR025980; ATP-Sase_PUA-like_dom.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR020792; SO4_adenylyltransferase_pro.
DR InterPro; IPR024951; Sulfurylase_cat_dom.
DR InterPro; IPR002650; Sulphate_adenylyltransferase.
DR Pfam; PF01747; ATP-sulfurylase; 1.
DR Pfam; PF14306; PUA_2; 1.
DR SUPFAM; SSF88697; SSF88697; 1.
DR TIGRFAMs; TIGR00339; sopT; 1.
PE 1: Evidence at protein level;
KW 3D-structure; ATP-binding; Nucleotide-binding; Nucleotidyltransferase;
KW Transferase.
FT CHAIN 1..437
FT /note="Sulfate adenylyltransferase"
FT /id="PRO_0000105941"
FT REGION 303..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 7..9
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 18..28
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 33..35
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 38..48
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 49..54
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 60..69
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 84..86
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 89..93
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 95..100
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 109..114
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 117..120
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 123..134
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 142..147
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 152..161
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 165..170
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 172..174
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 178..188
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 191..200
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 204..217
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 220..228
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 238..252
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 258..264
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 272..284
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 288..292
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 294..299
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 300..307
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 322..325
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 326..329
FT /evidence="ECO:0007829|PDB:1JHD"
FT STRAND 330..333
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 356..359
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 362..366
FT /evidence="ECO:0007829|PDB:1JHD"
FT TURN 373..375
FT /evidence="ECO:0007829|PDB:1JHD"
FT HELIX 378..386
FT /evidence="ECO:0007829|PDB:1JHD"
SQ SEQUENCE 437 AA; 48229 MW; 8E76C91631707352 CRC64;
MIKPVGSDEL KPLFVYDPEE HHKLSHEAES LPSVVISSQG PRVSSMMGAG YFSPAGFMNV
ADAMGAAEKM TLSDGSSSCS VLCLLENTDA IGDAKRIALR DPNVEGNPVL AVMDIEAIEE
VSDEQMAVMT DKVYRTTDMD HIGVKTFNSQ GRVAVSGPIQ VLNFSYFQAD FPDTFRTAVE
IRNEIKEHGW SKVVAFQTRN PMHRAHEELC RMPMESLDAD GVVVHMLLGK LKKGDIPAPV
RDAAIRTMAE VYFPPNTVMV TGYGFDMLYA GPREAVLHAY FRQNMGATHF IIGREPPAWV
TTTVPSTPRP SSMTKCQRAP WRSRSSCRPH GLLQEAEQDC DDARRAGSHQ GRLRTALRHQ
GREMLGQGIA PPPEFSRPEV AKILMDLLPV HQQLILIWFS GKTRPGVGRW RVFLCAAGAL
WPEAVAVANM EKRSSTG
