SAU12_ARATH
ID SAU12_ARATH Reviewed; 104 AA.
AC Q9SIG9;
DT 25-MAY-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Protein SMALL AUXIN UP-REGULATED RNA 12 {ECO:0000303|PubMed:29258424};
GN Name=SAUR12 {ECO:0000303|PubMed:29258424};
GN OrderedLocusNames=At2g21220 {ECO:0000312|Araport:AT2G21220};
GN ORFNames=F7O24.6 {ECO:0000312|EMBL:AAD24828.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, INDUCTION BY AUXIN AND
RP BRASSINOSTEROIDS, AND GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=29258424; DOI=10.1186/s12870-017-1210-4;
RA van Mourik H., van Dijk A.D.J., Stortenbeker N., Angenent G.C., Bemer M.;
RT "Divergent regulation of Arabidopsis SAUR genes: a focus on the SAUR10-
RT clade.";
RL BMC Plant Biol. 17:245-245(2017).
CC -!- FUNCTION: Provide a mechanistic link between auxin and plasma membrane
CC H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), and triggers PM
CC H(+)-ATPases activity by promoting phosphorylation of their C-terminal
CC autoinhibitory domain as a result of PP2C-D subfamily of type 2C
CC phosphatases inhibition, thus leading to the acidification of the
CC apoplast and the facilitation of solutes and water uptake to drive cell
CC expansion (By similarity). Triggers plant growth probably by promoting
CC cell elongation (By similarity). Regulates branch angles and bending
CC (By similarity). {ECO:0000250|UniProtKB:O65648,
CC ECO:0000250|UniProtKB:Q9SI60}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9FJG1};
CC Peripheral membrane protein {ECO:0000250|UniProtKB:Q9FJG1}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers and etiolated hypocotyls.
CC {ECO:0000269|PubMed:29258424}.
CC -!- DEVELOPMENTAL STAGE: Confined to styles of stage 13-16 flowers.
CC {ECO:0000269|PubMed:29258424}.
CC -!- INDUCTION: Induced by auxin (PubMed:29258424). Triggered by
CC brassinosteroids (PubMed:29258424). {ECO:0000269|PubMed:29258424}.
CC -!- SIMILARITY: Belongs to the ARG7 family. {ECO:0000305}.
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DR EMBL; AC007142; AAD24828.1; -; Genomic_DNA.
DR EMBL; AC006264; AAM15223.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07141.1; -; Genomic_DNA.
DR EMBL; BT005544; AAO63964.1; -; mRNA.
DR EMBL; AK118340; BAC42954.1; -; mRNA.
DR PIR; F84598; F84598.
DR RefSeq; NP_179718.1; NM_127694.3.
DR AlphaFoldDB; Q9SIG9; -.
DR STRING; 3702.AT2G21220.1; -.
DR PaxDb; Q9SIG9; -.
DR PRIDE; Q9SIG9; -.
DR EnsemblPlants; AT2G21220.1; AT2G21220.1; AT2G21220.
DR GeneID; 816659; -.
DR Gramene; AT2G21220.1; AT2G21220.1; AT2G21220.
DR KEGG; ath:AT2G21220; -.
DR Araport; AT2G21220; -.
DR TAIR; locus:2047117; AT2G21220.
DR eggNOG; ENOG502RZ3M; Eukaryota.
DR HOGENOM; CLU_098106_2_3_1; -.
DR InParanoid; Q9SIG9; -.
DR OMA; CYNDEDH; -.
DR OrthoDB; 1463651at2759; -.
DR PhylomeDB; Q9SIG9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIG9; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR GO; GO:0009733; P:response to auxin; IEP:UniProtKB.
DR GO; GO:0009741; P:response to brassinosteroid; IEP:UniProtKB.
DR InterPro; IPR003676; SAUR_fam.
DR PANTHER; PTHR31374; PTHR31374; 1.
DR Pfam; PF02519; Auxin_inducible; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Developmental protein; Growth regulation; Membrane;
KW Reference proteome.
FT CHAIN 1..104
FT /note="Protein SMALL AUXIN UP-REGULATED RNA 12"
FT /id="PRO_0000455146"
SQ SEQUENCE 104 AA; 11793 MW; C94A49EBB754104B CRC64;
MAVKRSSKLT QTAMLKQILK RCSSLAKNQC YDEDGLPVDV PKGHFPVYVG EKRSRYIVPI
SFLTHPKFKS LLQQAEEEFG FNHDMGLTIP CEEVVFRSLT SMIG
