SAU40_ARATH
ID SAU40_ARATH Reviewed; 134 AA.
AC O64538;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Auxin-responsive protein SAUR40 {ECO:0000305};
DE AltName: Full=Protein SMALL AUXIN UP RNA 40 {ECO:0000303|PubMed:12036261};
GN Name=SAUR40 {ECO:0000303|PubMed:12036261};
GN OrderedLocusNames=At1g79130 {ECO:0000312|Araport:AT1G79130};
GN ORFNames=YUP8H12R.25 {ECO:0000312|EMBL:AAC17066.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12036261; DOI=10.1023/a:1015207114117;
RA Hagen G., Guilfoyle T.J.;
RT "Auxin-responsive gene expression: genes, promoters and regulatory
RT factors.";
RL Plant Mol. Biol. 49:373-385(2002).
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=23759547; DOI=10.4161/psb.25283;
RA Qiu T., Chen Y., Li M., Kong Y., Zhu Y., Han N., Bian H., Zhu M., Wang J.;
RT "The tissue-specific and developmentally regulated expression patterns of
RT the SAUR41 subfamily of small auxin up RNA genes: potential implications.";
RL Plant Signal. Behav. 8:0-0(2013).
RN [6]
RP FUNCTION, AND INTERACTION WITH PP2C-D SUBFAMILY OF TYPE 2C PROTEIN
RP PHOSPHATASES.
RC STRAIN=cv. Columbia;
RX PubMed=24858935; DOI=10.1105/tpc.114.126037;
RA Spartz A.K., Ren H., Park M.Y., Grandt K.N., Lee S.H., Murphy A.S.,
RA Sussman M.R., Overvoorde P.J., Gray W.M.;
RT "SAUR inhibition of PP2C-D phosphatases activates plasma membrane H+-
RT ATPases to promote cell expansion in Arabidopsis.";
RL Plant Cell 26:2129-2142(2014).
CC -!- FUNCTION: Provide a mechanistic link between auxin and plasma membrane
CC H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), and triggers PM
CC H(+)-ATPases activity by promoting phosphorylation of their C-terminal
CC autoinhibitory domain as a result of PP2C-D subfamily of type 2C
CC phosphatases inhibition, thus leading to the acidification of the
CC apoplast and the facilitation of solutes and water uptake to drive cell
CC expansion (PubMed:24858935). Plays a role in the regulation of cell
CC expansion, root meristem patterning and auxin transport (By
CC similarity). {ECO:0000250|UniProtKB:Q9SA49,
CC ECO:0000269|PubMed:24858935}.
CC -!- SUBUNIT: Interacts with and inhibits PP2C-D subfamily of type 2C
CC phosphatases such as PP2C67/PP2C-D1. {ECO:0000269|PubMed:24858935}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23759547}.
CC -!- SIMILARITY: Belongs to the ARG7 family. {ECO:0000305}.
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DR EMBL; AC002986; AAC17066.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36208.1; -; Genomic_DNA.
DR EMBL; BT024795; ABD59133.1; -; mRNA.
DR PIR; T01042; T01042.
DR RefSeq; NP_178034.1; NM_106564.4.
DR AlphaFoldDB; O64538; -.
DR SMR; O64538; -.
DR IntAct; O64538; 2.
DR STRING; 3702.AT1G79130.1; -.
DR PaxDb; O64538; -.
DR PRIDE; O64538; -.
DR ProteomicsDB; 226644; -.
DR EnsemblPlants; AT1G79130.1; AT1G79130.1; AT1G79130.
DR GeneID; 844254; -.
DR Gramene; AT1G79130.1; AT1G79130.1; AT1G79130.
DR KEGG; ath:AT1G79130; -.
DR Araport; AT1G79130; -.
DR TAIR; locus:2207375; AT1G79130.
DR eggNOG; ENOG502S1QJ; Eukaryota.
DR HOGENOM; CLU_098106_7_1_1; -.
DR InParanoid; O64538; -.
DR OMA; CNVFVFE; -.
DR OrthoDB; 1455611at2759; -.
DR PhylomeDB; O64538; -.
DR PRO; PR:O64538; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O64538; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR InterPro; IPR003676; SAUR_fam.
DR PANTHER; PTHR31374; PTHR31374; 1.
DR Pfam; PF02519; Auxin_inducible; 1.
PE 1: Evidence at protein level;
KW Auxin signaling pathway; Cytoplasm; Developmental protein;
KW Growth regulation; Reference proteome.
FT CHAIN 1..134
FT /note="Auxin-responsive protein SAUR40"
FT /id="PRO_0000433069"
SQ SEQUENCE 134 AA; 14600 MW; CBDE03AEE62EAC0A CRC64;
MKPLIRRLSR IADSSSCNRN RSGDIHHPTS TYSSSVFLVK RATVASSVPS GHVPVNVGED
KERFVVSAEL LNHPVFVGLL NRSAQEYGYT QKGVLHIPCN VFVFEQVVES LRSGIADDTS
ELIASLSGED VSTE
