ID   SAUR_CUPNH              Reviewed;         252 AA.
AC   Q0K846;
DT   05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Probable transcriptional regulator SauR;
GN   Name=sauR; OrderedLocusNames=H16_A2746;
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
RN   [2]
RP   FUNCTION, AND GENE NAME.
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=20693281; DOI=10.1074/jbc.m110.127043;
RA   Weinitschke S., Hollemeyer K., Kusian B., Bowien B., Smits T.H., Cook A.M.;
RT   "Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and
RT   sulfoacetaldehyde in Cupriavidus necator H16.";
RL   J. Biol. Chem. 285:35249-35254(2010).
CC   -!- FUNCTION: May regulate transcription of the sauSTU operon.
CC       {ECO:0000269|PubMed:20693281}.
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DR   EMBL; AM260479; CAJ93825.1; -; Genomic_DNA.
DR   RefSeq; WP_010813655.1; NZ_CP039287.1.
DR   AlphaFoldDB; Q0K846; -.
DR   SMR; Q0K846; -.
DR   STRING; 381666.H16_A2746; -.
DR   EnsemblBacteria; CAJ93825; CAJ93825; H16_A2746.
DR   GeneID; 57644870; -.
DR   KEGG; reh:H16_A2746; -.
DR   eggNOG; COG1414; Bacteria.
DR   HOGENOM; CLU_062618_6_2_4; -.
DR   OMA; WPLRMHL; -.
DR   OrthoDB; 370329at2; -.
DR   Proteomes; UP000008210; Chromosome 1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..252
FT                   /note="Probable transcriptional regulator SauR"
FT                   /id="PRO_0000418825"
FT   DOMAIN          6..68
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
FT   DOMAIN          83..252
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00394"
FT   DNA_BIND        28..47
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
SQ   SEQUENCE   252 AA;  27718 MW;  2CB9B75E4E1D639E CRC64;
     MSNHSNAAAV RAFRILEILS AADGPLSLAA IVQAIELPKQ TVHRILKQLE STWLVSRTAG
     NRHYECSSRV RQLAVNVLMQ AGPAAARHAI LQQLVDKIGE TCNLTMLSGD DVVYLDRVET
     QWPLRMHLQP GSRVPLHCTA SGKLLLAFLP SAQRQRLVAS LPLRAHSAHT ITNAEALHAE
     LAETRQRRLG VNNQENLEGM IAVAVPVMRN RSRACAAIAV QVPMARMTMD QLMGFVPDLR
     LAADEMVKTF CE