ID   SBNO1_RAT               Reviewed;        1269 AA.
AC   Q5BJL5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Protein strawberry notch homolog 1;
GN   Name=Sbno1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RX   PubMed=15057822; DOI=10.1038/nature02426;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA   Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA   Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA   Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA   Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA   Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA   Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA   Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA   Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA   Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA   Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA   Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA   Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA   Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA   Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA   Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA   Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA   Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA   Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA   Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA   Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA   Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA   Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA   Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA   Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA   Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA   Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA   Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA   Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA   Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA   Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA   Mockrin S., Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into mammalian
RT   evolution.";
RL   Nature 428:493-521(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1089-1269.
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-178; SER-700 AND SER-701, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SIMILARITY: Belongs to the SBNO family. {ECO:0000305}.
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DR   EMBL; AABR03082113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC091433; AAH91433.1; -; mRNA.
DR   AlphaFoldDB; Q5BJL5; -.
DR   STRING; 10116.ENSRNOP00000054711; -.
DR   iPTMnet; Q5BJL5; -.
DR   PhosphoSitePlus; Q5BJL5; -.
DR   PaxDb; Q5BJL5; -.
DR   PRIDE; Q5BJL5; -.
DR   UCSC; RGD:1310005; rat.
DR   RGD; 1310005; Sbno1.
DR   eggNOG; KOG1513; Eukaryota.
DR   InParanoid; Q5BJL5; -.
DR   PRO; PR:Q5BJL5; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0031490; F:chromatin DNA binding; IBA:GO_Central.
DR   GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR   GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR026937; SBNO_Helicase_C_dom.
DR   InterPro; IPR026741; SNO.
DR   InterPro; IPR039187; SNO_AAA.
DR   PANTHER; PTHR12706; PTHR12706; 2.
DR   Pfam; PF13872; AAA_34; 1.
DR   Pfam; PF13871; Helicase_C_4; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
PE   1: Evidence at protein level;
KW   Acetylation; Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..1269
FT                   /note="Protein strawberry notch homolog 1"
FT                   /id="PRO_0000314557"
FT   REGION          21..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          652..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          719..746
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        690..711
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         113
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
FT   MOD_RES         126
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
FT   MOD_RES         178
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         377
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
FT   MOD_RES         656
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q689Z5"
FT   MOD_RES         657
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q689Z5"
FT   MOD_RES         661
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
FT   MOD_RES         700
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         701
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         1098
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
FT   MOD_RES         1262
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:A3KN83"
SQ   SEQUENCE   1269 AA;  140741 MW;  FEDD26493007AE08 CRC64;
     MVEPGQDLLL AALSESGISP NDLFDVDGGD AGLATPTPPS VQQQQPPSTT TFVLNQINQL
     PTLGSTIVMT KTPPATTNRQ TITLTKFIQT TANTRPSVSA PAVRNAIPPA PAKDQVQLKD
     LLKNNSLNEL MKLKPPANIA QPVATAAADV SNGAVKKESS NKEVARVWIN DMKMRSFSPT
     MKVPVVREED EPEEEDEEEM GHAETYAEYM PIKLKIGLRH PDAVVETSSL SSVTPPDVWY
     KTSISEETID NGWLSALQLE AVTYAAQQHE TFLPNGDRAG FLIGDGAGVG KGRTIAGIIY
     ENYLLSRKRA LWFSVSNDLK YDAERDLRDI GAKNILVHSL NKFKYGKISS KHNGSVKKGV
     IFATYSSLIG ESQSGGKYKT RLKQLLHWCG DDFDGVIVFD ECHKAKNLCP VGSSKPTKTG
     LAVLELQNKL PKARVVYASA TGASEPRNMA YMNRLGIWGE GTPFREFSDF IQAVERRGVG
     AMEIVAMDMK LRGMYIARQL SFTGVTFKIE EVLLSQSYVK MYNKAVKLWV IARERFQQAA
     DLIDAEQRMK KSMWGQFWSA HQRFFKYLCI ASKVKRVVQL AREEIKNGKC VVIGLQSTGE
     ARTLEALEEG GGELNDFVST AKGVLQSLIE KHFPAPDRKK LYSLLGIDLT APSNNSSPRD
     SAKKARKIGG LTGSSSDDSG SESDVSDNEE SDYESSKNMS SGDDDDFNPF RDDNSSLITS
     QDAVERAQQM KKDLLDKLEK LAEDLPPNTL DELIDELGGP ENVAEMTGRK GRVVSNDDGS
     ISYESRSELD VPVEILNITE KQRFMDGDKN IAIISEAASS GISLQADRRA KNQRRRVHMT
     LELPWSADRA IQQFGRTHRS NQVTAPEYVF LISELAGEQR FASIVAKRLE SLGALTHGDR
     RATESRDLSR FNFDNKYGRN ALEIVMKSIV NLDSPMVSPP PDYPGEFFKD VRQGLIGVGL
     INVEDRSGIL TLDKDYNNIG KFLNRILGME VHQQNALFQY FADTLTAVVQ NAKKNGRYDM
     GILDLGSGDE KVRKSDVKKF LTPGYSTSGH VELYTISVER GMSWDEATKI WAELTGPDDG
     FYLSLQIRNN KKTAILVKEV NPKKKLFLIY RPNTGKQLKL EIYADLKKKY KKVVSDDALV
     HWLDQYNSSA DTCTHAYWRG NCKKASLGLV CEIGLRCRTY YVLCGSVLSV WTKVEGVLAS
     VSGTNVKMQI VRLRTEDGQR IVGLIIPANC VSPLVNLLST SDQSQQLAVQ QKQLWQQHHP
     QSITNLSNV