SC16B_ARATH
ID SC16B_ARATH Reviewed; 1361 AA.
AC Q9FGK8;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Protein transport protein SEC16B homolog {ECO:0000305};
DE AltName: Full=Protein MAIGO 5 homolog {ECO:0000305};
GN Name=SEC16B {ECO:0000303|PubMed:24280388};
GN OrderedLocusNames=At5g47490 {ECO:0000312|Araport:AT5G47490};
GN ORFNames=MNJ7.8 {ECO:0000312|EMBL:BAB09075.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAB09075.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-46, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [4]
RP DISRUPTION PHENOTYPE.
RX PubMed=24280388; DOI=10.1105/tpc.113.118158;
RA Takagi J., Renna L., Takahashi H., Koumoto Y., Tamura K., Stefano G.,
RA Fukao Y., Kondo M., Nishimura M., Shimada T., Brandizzi F.,
RA Hara-Nishimura I.;
RT "MAIGO5 functions in protein export from Golgi-associated endoplasmic
RT reticulum exit sites in Arabidopsis.";
RL Plant Cell 25:4658-4675(2013).
CC -!- FUNCTION: Required for protein transport from the endoplasmic reticulum
CC to the Golgi apparatus. {ECO:0000303|PubMed:24280388}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q9FGK9}.
CC Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9FGK9}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:24280388}.
CC -!- SIMILARITY: Belongs to the SEC16 family. {ECO:0000305}.
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DR EMBL; AB025628; BAB09075.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95525.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68390.1; -; Genomic_DNA.
DR RefSeq; NP_001318753.1; NM_001344728.1.
DR RefSeq; NP_199560.1; NM_124122.3.
DR AlphaFoldDB; Q9FGK8; -.
DR STRING; 3702.AT5G47490.1; -.
DR iPTMnet; Q9FGK8; -.
DR PaxDb; Q9FGK8; -.
DR PRIDE; Q9FGK8; -.
DR ProteomicsDB; 232740; -.
DR EnsemblPlants; AT5G47490.1; AT5G47490.1; AT5G47490.
DR EnsemblPlants; AT5G47490.2; AT5G47490.2; AT5G47490.
DR GeneID; 834799; -.
DR Gramene; AT5G47490.1; AT5G47490.1; AT5G47490.
DR Gramene; AT5G47490.2; AT5G47490.2; AT5G47490.
DR KEGG; ath:AT5G47490; -.
DR Araport; AT5G47490; -.
DR TAIR; locus:2169008; AT5G47490.
DR eggNOG; KOG1913; Eukaryota.
DR HOGENOM; CLU_002428_1_0_1; -.
DR InParanoid; Q9FGK8; -.
DR OMA; SENQMQA; -.
DR OrthoDB; 106114at2759; -.
DR PhylomeDB; Q9FGK8; -.
DR PRO; PR:Q9FGK8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGK8; baseline and differential.
DR Genevisible; Q9FGK8; AT.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IBA:GO_Central.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR GO; GO:0070973; P:protein localization to endoplasmic reticulum exit site; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402; PTHR13402; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Phosphoprotein;
KW Protein transport; Reference proteome; Transport.
FT CHAIN 1..1361
FT /note="Protein transport protein SEC16B homolog"
FT /id="PRO_0000430537"
FT REGION 82..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1062
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1163..1204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1216..1235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1306..1361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 996..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1163..1203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1306..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 46
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 1361 AA; 147817 MW; 449FC1D6ED2D9162 CRC64;
MASASQFLLE DQTDEDFFDK LVDDAYSPTE AQASSSVTEL KFDDESDSDD IRAFSNLSIG
KDPLGGGDGT LNEAILGNDV ANEGASGSVG EDEPSSIAPE AVQFPHSDAR ELRDDEMRSE
VADMPLSETA KECTIVNEPG IPGVKELDWG SFDADLSVND GRGFGSYSDF FTELDATAGN
LQGKADVAVA TGGNLVANDT NNTSVGFEQH QGQLHHDSAS GQYVDNSQSW ENLYPGWKYD
ASTGQWFQVD GHDASMNSQE SYENSTSNWE NVAANNSDVA YQRQSTASAV AGTVENVSTW
NQVSQVSNGY PEHMVFDSQY PGWYYDTIAQ EWRSLDSYNQ AFQTTGQAND QQVQNGNSFT
AVDHSRESNV HDVYDKNQIL RTQKFDIQSQ HGSWDQSYYD KNQQATNMWQ PENAGAAEAA
VTPASLSNSG GNQQVNNLYS TGPVAEQFKP YESGVQSFIP QHMNVANVTQ NGPMSFSNGF
YSRQESVDDA PQSFQSSQLF SPSAGRSSDG RPPHALVNFG FGGKLILMKD DSGSLQNSSF
GSQKGTGGSS ISVLNLAEVI SGSASYSSLG ENSLSYFSCL DQQSLPGPLV GGNVGSKDLH
KWLDERILNC ESSYMDFSRG KLLKMLLSLL RISCQYYGKL RSPFGSDALQ KETDSAEAAV
AKLFAIAKED GVQNGYAPIS QCLQHLPPES QMQVTASEVQ NLLASGRKME ALQCAQEGHL
WGPALVIAAQ LGQQFYVDTV KQMALRQLVP GSPLRTLCLL VAGQPAEVFS TGSTSDISFP
GSVNLPPQQP QFGCSSMLDS WEENLGIITA NRTTDDELVI THLGDCMWKE RGEIIAAHIC
YLIADKNFDT YSDTARLCLV GADHWKYPRT YASPEAIQRT ELYEYSKTLG NSQYTLLTFQ
PYKVMYAHML AEVGKLSTAQ KYCQAVLKCL KTGRSPEVEM WKQFVSSLEE RIRIHQQGGY
TANLHPEKLV GVLLNFFGSK THRPVGGMPP PAPHSTKGNL QGNEYQHQQQ EATKLAYSQS
VNTMSSLMPP ASVEPTHESG GSGRRMAVHT RSVSEPDFGR TPIQEMADSS KEKAVDGVTK
LKSSGSVAGS RFSRFGFGIF KDTVGRVLAR SSKEAKLGAE NQFYYDDKLK RWVERGVEPP
AEEAALPPPP TIGAFQNNSL GYENKSDMIP SNGNWSSGGP TPSENSSGIP PISHGSNQFS
ARGRTGVRAR YVDTYNPPGR GNSHTMIPSP SVQTAKPPIP AKAKFFVPAA PASFSNDQAM
EPAAAETRQE EISADEVVAS SGAPPPMMMQ RYPSMDNIQR NGLGISVNGD NHQPPTSRRT
ASWSGNFNTS FTPPTSPSTF KPVLLNSSSS SLGEELQEVE L
