ID   SC1_SCHCO               Reviewed;         109 AA.
AC   P04158;
DT   01-NOV-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 2.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Fruiting body protein SC1;
DE   AltName: Full=Hydrophobin SC1;
DE   Flags: Precursor;
GN   Name=SC1; Synonyms=1G2;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16453552; DOI=10.1002/j.1460-2075.1984.tb02097.x;
RA   Dons J.J.M., Mulder G.H., Rouwendal G.J.A., Springer J., Bremer W.,
RA   Wessels J.G.H.;
RT   "Sequence analysis of a split gene involved in fruiting from the fungus
RT   Schizophyllum commune.";
RL   EMBO J. 3:2101-2106(1984).
RN   [2]
RP   SEQUENCE REVISION.
RX   PubMed=2401401; DOI=10.1016/0378-1119(90)90180-y;
RA   Schuren F.H.J., Wessels J.G.H.;
RT   "Two genes specifically expressed in fruiting dikaryons of Schizophyllum
RT   commune: homologies with a gene not regulated by mating-type genes.";
RL   Gene 90:199-205(1990).
CC   -!- FUNCTION: Contributes to surface hydrophobicity, which is important for
CC       processes such as association of hyphae in reproductive structures,
CC       dispersal of aerial spores and adhesion of pathogens to host
CC       structures.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall. Secreted. Note=Secreted in
CC       aqueous environment.
CC   -!- DEVELOPMENTAL STAGE: Is abundantly expressed and accumulates in the
CC       walls of developing fruiting bodies (only in fruiting dikaryons).
CC   -!- SIMILARITY: Belongs to the fungal hydrophobin family. {ECO:0000305}.
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DR   EMBL; X00788; CAA25366.1; ALT_SEQ; Genomic_DNA.
DR   PIR; A04506; COSJS.
DR   PIR; JU0321; JU0321.
DR   AlphaFoldDB; P04158; -.
DR   SMR; P04158; -.
DR   OMA; CCENNNX; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009277; C:fungal-type cell wall; IEA:InterPro.
DR   GO; GO:0005199; F:structural constituent of cell wall; IEA:InterPro.
DR   InterPro; IPR001338; Hydrophobin.
DR   InterPro; IPR019778; Hydrophobin_CS.
DR   Pfam; PF01185; Hydrophobin; 1.
DR   SMART; SM00075; HYDRO; 1.
DR   PROSITE; PS00956; HYDROPHOBIN; 1.
PE   2: Evidence at transcript level;
KW   Cell wall; Disulfide bond; Fruiting body; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..109
FT                   /note="Fruiting body protein SC1"
FT                   /id="PRO_0000013512"
FT   DISULFID        27..88
FT                   /evidence="ECO:0000250"
FT   DISULFID        34..82
FT                   /evidence="ECO:0000250"
FT   DISULFID        35..69
FT                   /evidence="ECO:0000250"
FT   DISULFID        89..102
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   109 AA;  10803 MW;  680F8E22BDFA0FEE CRC64;
     MRFSLAILAL PVLAAATAVP RGGASKCNSG PVQCCNTLVD TKDKHQTNIV GALLGLDLGS
     LTGLAGVNCS PVSVIGVGGN SCSTQTVCCE GTQFNGLVNV GCTPINVGL