ID   SC24A_ARATH             Reviewed;        1038 AA.
AC   Q9SFU0; Q56WS8; Q8L7A7;
DT   21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 2.
DT   25-MAY-2022, entry version 133.
DE   RecName: Full=Protein transport protein Sec24-like At3g07100;
GN   OrderedLocusNames=At3g07100; ORFNames=T1B9.25;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 751-1038.
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the COPII coat, that covers ER-derived vesicles
CC       involved in transport from the endoplasmic reticulum to the Golgi
CC       apparatus. COPII is composed of at least five proteins: the SEC23/24
CC       complex, the SEC13/31 complex, and the protein SAR1. Acts in the
CC       cytoplasm to promote the transport of secretory, plasma membrane, and
CC       vacuolar proteins from the endoplasmic reticulum to the Golgi complex
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:O95486}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:O95486}. Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:O95486}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:O95486}.
CC   -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF20236.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAD94443.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC012395; AAF20236.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE74498.1; -; Genomic_DNA.
DR   EMBL; AY136376; AAM97042.1; -; mRNA.
DR   EMBL; BT000173; AAN15492.1; -; mRNA.
DR   EMBL; AK221955; BAD94443.1; ALT_INIT; mRNA.
DR   RefSeq; NP_187366.2; NM_111590.4.
DR   AlphaFoldDB; Q9SFU0; -.
DR   SMR; Q9SFU0; -.
DR   BioGRID; 5231; 8.
DR   STRING; 3702.AT3G07100.1; -.
DR   PaxDb; Q9SFU0; -.
DR   PRIDE; Q9SFU0; -.
DR   ProteomicsDB; 232847; -.
DR   EnsemblPlants; AT3G07100.1; AT3G07100.1; AT3G07100.
DR   GeneID; 819896; -.
DR   Gramene; AT3G07100.1; AT3G07100.1; AT3G07100.
DR   KEGG; ath:AT3G07100; -.
DR   Araport; AT3G07100; -.
DR   TAIR; locus:2098545; AT3G07100.
DR   eggNOG; KOG1985; Eukaryota.
DR   HOGENOM; CLU_004589_4_1_1; -.
DR   InParanoid; Q9SFU0; -.
DR   OMA; TFPRDQS; -.
DR   OrthoDB; 330236at2759; -.
DR   PhylomeDB; Q9SFU0; -.
DR   PRO; PR:Q9SFU0; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9SFU0; baseline and differential.
DR   Genevisible; Q9SFU0; AT.
DR   GO; GO:0030127; C:COPII vesicle coat; IBA:GO_Central.
DR   GO; GO:0070971; C:endoplasmic reticulum exit site; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR   GO; GO:0090110; P:COPII-coated vesicle cargo loading; IBA:GO_Central.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:TAIR.
DR   GO; GO:0080119; P:ER body organization; IMP:TAIR.
DR   GO; GO:0007030; P:Golgi organization; IMP:TAIR.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0048232; P:male gamete generation; IMP:TAIR.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:TAIR.
DR   GO; GO:0008361; P:regulation of cell size; IMP:TAIR.
DR   CDD; cd01479; Sec24-like; 1.
DR   Gene3D; 3.40.20.10; -; 1.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR007123; Gelsolin-like_dom.
DR   InterPro; IPR036180; Gelsolin-like_dom_sf.
DR   InterPro; IPR006900; Sec23/24_helical_dom.
DR   InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR   InterPro; IPR006896; Sec23/24_trunk_dom.
DR   InterPro; IPR012990; Sec23_24_beta_S.
DR   InterPro; IPR041742; Sec24-like_trunk_dom.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   InterPro; IPR006895; Znf_Sec23_Sec24.
DR   InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR   Pfam; PF00626; Gelsolin; 1.
DR   Pfam; PF08033; Sec23_BS; 1.
DR   Pfam; PF04815; Sec23_helical; 1.
DR   Pfam; PF04811; Sec23_trunk; 1.
DR   Pfam; PF04810; zf-Sec23_Sec24; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   SUPFAM; SSF81811; SSF81811; 1.
DR   SUPFAM; SSF82754; SSF82754; 1.
DR   SUPFAM; SSF82919; SSF82919; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..1038
FT                   /note="Protein transport protein Sec24-like At3g07100"
FT                   /id="PRO_0000205158"
FT   REGION          1..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..396
FT                   /note="Zinc finger-like"
FT   COMPBIAS        18..33
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..74
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..136
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..238
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1038 AA;  113960 MW;  C45945D37400FD29 CRC64;
     MGTENQGYPN FPARPASSPF ASAPPPGIPP QSGGPPTGSE AVGFRPFTPS ASQPTRPFTA
     SGPPPAPPVG TMRPGQPSPF VSQIPGSRPP PPSSNSFPSP AYGPPGGAPF QRFPSPPFPT
     TQNPPQGPPP PQTLAGHLSP PMSLRPQQPM APVAMGPPPQ STTSGLPGAN AYPPATDYHM
     PARPGFQQSM PPVTPSYPGV GGSQPSFPGY PSKQVLQAPT PFQTSQGPPG PPPVSSYPPH
     TGGFAQRPNM AAQQNLHPNY APPPSNVQGL TEDFNSLSLS SIPGSLEPGL DHKSFPRPLD
     GDVEPNSFAE MYPMNCHSRY LRLTTSAIPN SQSLASRWHL PLGAVVCPLA ETPEGEEVPL
     IDFGSTGIIR CRRCRTYVNP FVTFTDSGRK WRCNICSMLN DVPGEYFSHL DATGRRMDMD
     QRPELTKGSV EIIAPTEYMV RPPMPPIYFF LIDVSISATK SGMLEVVAQT IKSCLDNLPG
     YPRTQIGFIT YDSTLHFYNM KSSLSQPQMM VVSDLDDIFV PLPDDLLVNL SESRTVVDAF
     LDSLPLMFQD NFNVESAFGP ALRAAFMVMN QLGGKLLIFQ NSLPSLGAGR LKLRGDDPRV
     YGTDKEYALR VAEDPFYKQM AADCTKFQIG INVYAFSDKY TDIASLGTLA KYTGGQVYYY
     PGFQSSVHGD KLRHELARDL TRETAWEAVM RIRCGKGIRF SSYHGNFMLR STDLLALPAV
     DCDKAYAMQL SLEETLLTSQ TVYFQVALLY TASCGERRIR VHTSVAPVVT DLGEMYRQAD
     TGSIVSLYAR LAIEKSLSAK LDDARNAIQQ KIVKALKEYR NLHAVQHRLG SRLVYPESLK
     FLPLYGLAIT KSTPLLGGPA DTSLDERCAA GFTMMALPVK KLLKLLYPNL FRVDEWLLKP
     SAAHDDFKDV LRRLPLAAES LDSRGLYIYD DGFRLVLWFG RMLSPDIAKN LLGVDFAADL
     SRVTFQEQEN GMSKKLMRLV KKLRESDPSY HPMCFLVRQG EQPREGFLLL RNLIEDQMGG
     SSGYVDWILQ LHRQVQQN