SC2B2_HUMAN
ID SC2B2_HUMAN Reviewed; 96 AA.
AC Q4G0G5;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Secretoglobin family 2B member 2;
DE AltName: Full=Secretoglobin-like protein;
DE Flags: Precursor;
GN Name=SCGB2B2; Synonyms=SCGB4A2, SCGBL;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q4G0G5; Q9UHD9: UBQLN2; NbExp=3; IntAct=EBI-12019232, EBI-947187;
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the secretoglobin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC093909; AAH93909.1; -; mRNA.
DR EMBL; BC093935; AAH93935.1; -; mRNA.
DR CCDS; CCDS32989.1; -.
DR RefSeq; NP_001020762.1; NM_001025591.3.
DR AlphaFoldDB; Q4G0G5; -.
DR SMR; Q4G0G5; -.
DR BioGRID; 129862; 2.
DR IntAct; Q4G0G5; 1.
DR STRING; 9606.ENSP00000469876; -.
DR BioMuta; SCGB2B2; -.
DR DMDM; 121943820; -.
DR PaxDb; Q4G0G5; -.
DR PRIDE; Q4G0G5; -.
DR Antibodypedia; 44378; 15 antibodies from 10 providers.
DR DNASU; 284402; -.
DR Ensembl; ENST00000379204.2; ENSP00000368502.2; ENSG00000205209.8.
DR Ensembl; ENST00000601241.6; ENSP00000469876.1; ENSG00000205209.8.
DR GeneID; 284402; -.
DR KEGG; hsa:284402; -.
DR MANE-Select; ENST00000601241.6; ENSP00000469876.1; NM_001025591.4; NP_001020762.1.
DR UCSC; uc002nvn.4; human.
DR CTD; 284402; -.
DR GeneCards; SCGB2B2; -.
DR HGNC; HGNC:27616; SCGB2B2.
DR HPA; ENSG00000205209; Tissue enhanced (pancreas).
DR MIM; 615063; gene.
DR neXtProt; NX_Q4G0G5; -.
DR OpenTargets; ENSG00000205209; -.
DR PharmGKB; PA164725574; -.
DR VEuPathDB; HostDB:ENSG00000205209; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00410000028752; -.
DR HOGENOM; CLU_2412691_0_0_1; -.
DR InParanoid; Q4G0G5; -.
DR OMA; QCYRNIS; -.
DR OrthoDB; 1536318at2759; -.
DR PhylomeDB; Q4G0G5; -.
DR TreeFam; TF338526; -.
DR PathwayCommons; Q4G0G5; -.
DR SignaLink; Q4G0G5; -.
DR BioGRID-ORCS; 284402; 12 hits in 1047 CRISPR screens.
DR ChiTaRS; SCGB2B2; human.
DR GenomeRNAi; 284402; -.
DR Pharos; Q4G0G5; Tdark.
DR PRO; PR:Q4G0G5; -.
DR Proteomes; UP000005640; Chromosome 19.
DR RNAct; Q4G0G5; protein.
DR Bgee; ENSG00000205209; Expressed in right lobe of liver and 95 other tissues.
DR Genevisible; Q4G0G5; HS.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR016126; Secretoglobin.
DR InterPro; IPR035960; Secretoglobin_sf.
DR Pfam; PF01099; Uteroglobin; 1.
DR SUPFAM; SSF48201; SSF48201; 1.
DR PROSITE; PS51311; SCGB; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..96
FT /note="Secretoglobin family 2B member 2"
FT /id="PRO_0000342373"
SQ SEQUENCE 96 AA; 10563 MW; CCFF596BC717A7AF CRC64;
MRVTSATCAL LLALICSVQL GDACLDIDKL LANVVFDVSQ DLLKEELARY NPSPLTEESF
LNVQQCFANV SVTERFAHSV VIKKILQSND CIEAAF