SC31B_ARATH
ID SC31B_ARATH Reviewed; 1104 AA.
AC Q8L611; Q9LY69;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 149.
DE RecName: Full=Protein transport protein SEC31 homolog B {ECO:0000305};
DE AltName: Full=SEC31-like protein B {ECO:0000305};
GN Name=SEC31B {ECO:0000303|PubMed:24280388};
GN OrderedLocusNames=At3g63460 {ECO:0000312|Araport:AT3G63460};
GN ORFNames=MAA21.90 {ECO:0000312|EMBL:CAB87799.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAM20553.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-526, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [5]
RP INTERACTION WITH SEC13A AND SEC13B.
RX PubMed=24280388; DOI=10.1105/tpc.113.118158;
RA Takagi J., Renna L., Takahashi H., Koumoto Y., Tamura K., Stefano G.,
RA Fukao Y., Kondo M., Nishimura M., Shimada T., Brandizzi F.,
RA Hara-Nishimura I.;
RT "MAIGO5 functions in protein export from Golgi-associated endoplasmic
RT reticulum exit sites in Arabidopsis.";
RL Plant Cell 25:4658-4675(2013).
CC -!- FUNCTION: Required for protein transport from the endoplasmic reticulum
CC to the Golgi apparatus. {ECO:0000305|PubMed:24280388}.
CC -!- SUBUNIT: Interacts with SEC13A and SEC13B.
CC {ECO:0000269|PubMed:24280388}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000305|PubMed:24280388}.
CC Endoplasmic reticulum {ECO:0000305|PubMed:24280388}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q8L611-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the WD repeat SEC31 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB87799.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL163818; CAB87799.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE80486.1; -; Genomic_DNA.
DR EMBL; AY099702; AAM20553.1; -; mRNA.
DR EMBL; BT008435; AAP37794.1; -; mRNA.
DR PIR; T49187; T49187.
DR RefSeq; NP_851024.1; NM_180693.2. [Q8L611-1]
DR AlphaFoldDB; Q8L611; -.
DR SMR; Q8L611; -.
DR BioGRID; 10835; 11.
DR IntAct; Q8L611; 2.
DR STRING; 3702.AT3G63460.1; -.
DR iPTMnet; Q8L611; -.
DR MetOSite; Q8L611; -.
DR PaxDb; Q8L611; -.
DR PRIDE; Q8L611; -.
DR ProMEX; Q8L611; -.
DR ProteomicsDB; 226671; -. [Q8L611-1]
DR EnsemblPlants; AT3G63460.1; AT3G63460.1; AT3G63460. [Q8L611-1]
DR GeneID; 825521; -.
DR Gramene; AT3G63460.1; AT3G63460.1; AT3G63460. [Q8L611-1]
DR KEGG; ath:AT3G63460; -.
DR Araport; AT3G63460; -.
DR TAIR; locus:2087433; AT3G63460.
DR eggNOG; KOG0307; Eukaryota.
DR InParanoid; Q8L611; -.
DR OrthoDB; 100998at2759; -.
DR PhylomeDB; Q8L611; -.
DR PRO; PR:Q8L611; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8L611; baseline and differential.
DR Genevisible; Q8L611; AT.
DR GO; GO:0030127; C:COPII vesicle coat; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005198; F:structural molecule activity; IBA:GO_Central.
DR GO; GO:0090110; P:COPII-coated vesicle cargo loading; IBA:GO_Central.
DR GO; GO:0007029; P:endoplasmic reticulum organization; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR040251; SEC31-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13923; PTHR13923; 1.
DR Pfam; PF12931; Sec16_C; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Endoplasmic reticulum; ER-Golgi transport;
KW Golgi apparatus; Phosphoprotein; Protein transport; Reference proteome;
KW Repeat; Transport; WD repeat.
FT CHAIN 1..1104
FT /note="Protein transport protein SEC31 homolog B"
FT /id="PRO_0000430541"
FT REPEAT 5..45
FT /note="WD 1"
FT /evidence="ECO:0000255"
FT REPEAT 62..109
FT /note="WD 2"
FT /evidence="ECO:0000255"
FT REPEAT 120..160
FT /note="WD 3"
FT /evidence="ECO:0000255"
FT REPEAT 170..210
FT /note="WD 4"
FT /evidence="ECO:0000255"
FT REPEAT 214..257
FT /note="WD 5"
FT /evidence="ECO:0000255"
FT REPEAT 261..301
FT /note="WD 6"
FT /evidence="ECO:0000255"
FT REPEAT 304..344
FT /note="WD 7"
FT /evidence="ECO:0000255"
FT REPEAT 662..707
FT /note="WD 8"
FT /evidence="ECO:0000255"
FT REGION 527..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 952..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..811
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 526
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 1104 AA; 119875 MW; 2C0BDBBE59607634 CRC64;
MACIKGVGRS ASVALAPDAP YMAAGTMAGA VDLSFSSSAN LEIFKLDFQS DDRDLPLVGE
IPSSERFNRL AWGRNGSGSE EFALGLIAGG LVDGNIDLWN PLSLIGSQPS ENALVGHLSV
HKGPVRGLEF NAISSNLLAS GADDGEICIW DLLKPSEPSH FPLLKGSGSA TQGEISFISW
NRKVQQILAS TSYNGTTVIW DLRKQKPIIN FADSVRRRCS VLQWNPNVTT QIMVASDDDS
SPTLKLWDMR NIMSPVREFT GHQRGVIAME WCPSDSSYLL TCAKDNRTIC WDTNTAEIVA
ELPAGNNWNF DVHWYPKIPG VISASSFDGK IGIYNIEGCS RYGVEENNFG TAPLKAPKWY
KRPVGASFGF GGKLVSCHAR APAKGTSSIL SEVFLHSLVT EQSLVSRTSE FEAAIENGDM
TSLRGLCEKK SEETESEEEK ETWGLLKIMF EEEGTSRTKL ISHLGFTLPV AEKDQAVDGL
SSDLNGIRLE DTAADALDLD DSNEAAAFAM DNGEDFFNNF PAKPDTPVST SAKDFMPSDT
DFSTKGEETQ EMQEEEEESS DPVFDNAIQR ALIVGDYKEA VDQCITANKM ADALVIAHVG
GTALWESTRE KYLKTSSAPY MKVVSAMVNN DLRSLIYTRS HKFWKETLAL LCTFAQGEQW
TTLCDALASK LMAAGNTLAA VLCYICAGNV DRTVEIWSRS LANERDGRSY AELLQDLMEK
TLVLALATGN KKFSASLCKL FESYAEILAS QGLLTTAMKY LKVLDSGGLS PELSILRDRI
SLSAEPETNT TASGNTQPQS TMPYNQEPTQ AQPNVLANPY DNQYQQPYTD SYYVPQVSHP
PMQQPTMFMP HQAQPAPQPS FTPAPTSNAQ PSMRTTFVPS TPPALKNADQ YQQPTMSSHS
FTGPSNNAYP VPPGPGQYAP SGPSQLGQYP NPKMPQVVAP AAGPIGFTPM ATPGVAPRSV
QPASPPTQQA AAQAAPAPAT PPPTVQTADT SNVPAHQKPV IATLTRLFNE TSEALGGARA
NTTKKREIED NSRKLGALFV KLNSGDISKN AADKLAQLCQ ALDNNDFSTA LQIQVLLTTS
EWDECNFWLA TLKRMMVKAR QNVR
