ID   SC61G_DICDI             Reviewed;          69 AA.
AC   Q54JV6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Protein transport protein Sec61 subunit gamma;
GN   Name=sec61g; ORFNames=DDB_G0287777;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC       reticulum. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC       SEC61-gamma. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Single-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
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DR   EMBL; AAFI02000104; EAL63535.1; -; Genomic_DNA.
DR   RefSeq; XP_637046.1; XM_631954.1.
DR   AlphaFoldDB; Q54JV6; -.
DR   SMR; Q54JV6; -.
DR   STRING; 44689.DDB0235195; -.
DR   PaxDb; Q54JV6; -.
DR   EnsemblProtists; EAL63535; EAL63535; DDB_G0287777.
DR   GeneID; 8626300; -.
DR   KEGG; ddi:DDB_G0287777; -.
DR   dictyBase; DDB_G0287777; sec61g.
DR   eggNOG; KOG3498; Eukaryota.
DR   HOGENOM; CLU_167752_2_0_1; -.
DR   InParanoid; Q54JV6; -.
DR   OMA; RDGNQFL; -.
DR   PhylomeDB; Q54JV6; -.
DR   Reactome; R-DDI-9609523; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
DR   PRO; PR:Q54JV6; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071261; C:Ssh1 translocon complex; IBA:GO_Central.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR   Gene3D; 1.20.5.820; -; 1.
DR   HAMAP; MF_00422; SecE; 1.
DR   InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR   InterPro; IPR008158; Translocase_Sec61-g.
DR   InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR   Pfam; PF00584; SecE; 1.
DR   SUPFAM; SSF103456; SSF103456; 1.
DR   TIGRFAMs; TIGR00327; secE_euk_arch; 1.
DR   PROSITE; PS01067; SECE_SEC61G; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..69
FT                   /note="Protein transport protein Sec61 subunit gamma"
FT                   /id="PRO_0000328021"
FT   TOPO_DOM        1..40
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        62..69
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   69 AA;  7621 MW;  1580D7EB4D514A0E CRC64;
     MDILEETAAP LKDFAKNSIR LFKKCTKPDA QEFQKIALAT LIGFAIMGFI GFFVKLIHIP
     INNILVGGV