SC61G_ENCCU
ID SC61G_ENCCU Reviewed; 72 AA.
AC Q8SRW9;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Probable protein transport protein Sec61 subunit gamma;
GN OrderedLocusNames=ECU05_0885;
OS Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=284813;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB-M1;
RX PubMed=11719806; DOI=10.1038/35106579;
RA Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA Vivares C.P.;
RT "Genome sequence and gene compaction of the eukaryote parasite
RT Encephalitozoon cuniculi.";
RL Nature 414:450-453(2001).
CC -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC reticulum. {ECO:0000305}.
CC -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC SEC61-gamma. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Single-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
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DR EMBL; AL590445; CAD26608.1; -; Genomic_DNA.
DR RefSeq; NP_597431.1; NM_001041297.1.
DR AlphaFoldDB; Q8SRW9; -.
DR SMR; Q8SRW9; -.
DR STRING; 284813.Q8SRW9; -.
DR GeneID; 859097; -.
DR KEGG; ecu:ECU05_0885; -.
DR VEuPathDB; MicrosporidiaDB:ECU05_0885; -.
DR HOGENOM; CLU_167752_2_1_1; -.
DR InParanoid; Q8SRW9; -.
DR OMA; HFISKCE; -.
DR OrthoDB; 1623399at2759; -.
DR Proteomes; UP000000819; Chromosome V.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR Gene3D; 1.20.5.820; -; 1.
DR HAMAP; MF_00422; SecE; 1.
DR InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR InterPro; IPR008158; Translocase_Sec61-g.
DR InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR Pfam; PF00584; SecE; 1.
DR SUPFAM; SSF103456; SSF103456; 1.
DR TIGRFAMs; TIGR00327; secE_euk_arch; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW Translocation; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..72
FT /note="Probable protein transport protein Sec61 subunit
FT gamma"
FT /id="PRO_0000104208"
FT TOPO_DOM 1..40
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 62..72
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 72 AA; 8040 MW; 95864B9EDC88AA86 CRC64;
MSQKLQKPSF LSEYLRSIRL FSKKCVRPSG KELSMSIKRH AIGIGFLGIL GYAIKLIHIP
INNIIVSSPG KE