ID   SC61G_HARAN             Reviewed;          68 AA.
AC   Q7T207;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Protein transport protein Sec61 subunit gamma;
GN   Name=sec61g;
OS   Harpagifer antarcticus (Antarctic spiny plunderfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Notothenioidei; Harpagiferidae; Harpagifer.
OX   NCBI_TaxID=43256;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=12771183; DOI=10.1242/jcs.00597;
RA   Romisch K., Collie N., Soto N., Logue J., Lindsay M., Scheper W.,
RA   Cheng C.-H.C.;
RT   "Protein translocation across the endoplasmic reticulum membrane in cold-
RT   adapted organisms.";
RL   J. Cell Sci. 116:2875-2883(2003).
CC   -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC       reticulum and multi-pass membrane protein biogenesis.
CC       {ECO:0000250|UniProtKB:P60059}.
CC   -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC       SEC61-gamma (By similarity). Component of the ribosome-associated ER
CC       translocon complex (By similarity). {ECO:0000250|UniProtKB:P60058,
CC       ECO:0000250|UniProtKB:P60059}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:P60058}; Single-pass membrane protein
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
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DR   EMBL; AY258259; AAP74549.1; -; mRNA.
DR   AlphaFoldDB; Q7T207; -.
DR   SMR; Q7T207; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
DR   Gene3D; 1.20.5.820; -; 1.
DR   HAMAP; MF_00422; SecE; 1.
DR   InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR   InterPro; IPR008158; Translocase_Sec61-g.
DR   InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR   Pfam; PF00584; SecE; 1.
DR   SUPFAM; SSF103456; SSF103456; 1.
DR   TIGRFAMs; TIGR00327; secE_euk_arch; 1.
DR   PROSITE; PS01067; SECE_SEC61G; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Translocation;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..68
FT                   /note="Protein transport protein Sec61 subunit gamma"
FT                   /id="PRO_0000104199"
FT   TOPO_DOM        1..32
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        62..68
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   68 AA;  7727 MW;  07701C0A22548561 CRC64;
     MDQVMQFVEP SRQFVKDSIR LVKRCTKPDR KEFQKVAMAT AIGFAIMGFI GFFVKLIHIP
     INNIIVGG