ID   SC61G_NEUCR             Reviewed;          70 AA.
AC   Q9C2D4;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Probable protein transport protein Sec61 subunit gamma;
GN   ORFNames=9G6.310, NCU04127;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12655011; DOI=10.1093/nar/gkg293;
RA   Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA   Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT   "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT   genome sequence.";
RL   Nucleic Acids Res. 31:1944-1954(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC       reticulum. {ECO:0000305}.
CC   -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC       SEC61-gamma. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Single-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
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DR   EMBL; AL513463; CAC28779.2; -; Genomic_DNA.
DR   EMBL; CM002240; EAA32047.1; -; Genomic_DNA.
DR   RefSeq; XP_961283.1; XM_956190.3.
DR   AlphaFoldDB; Q9C2D4; -.
DR   SMR; Q9C2D4; -.
DR   STRING; 5141.EFNCRP00000003802; -.
DR   EnsemblFungi; EAA32047; EAA32047; NCU04127.
DR   GeneID; 3877447; -.
DR   KEGG; ncr:NCU04127; -.
DR   VEuPathDB; FungiDB:NCU04127; -.
DR   HOGENOM; CLU_167752_2_0_1; -.
DR   InParanoid; Q9C2D4; -.
DR   OMA; RDGNQFL; -.
DR   Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071261; C:Ssh1 translocon complex; IBA:GO_Central.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR   Gene3D; 1.20.5.820; -; 1.
DR   HAMAP; MF_00422; SecE; 1.
DR   InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR   InterPro; IPR008158; Translocase_Sec61-g.
DR   InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR   Pfam; PF00584; SecE; 1.
DR   SUPFAM; SSF103456; SSF103456; 1.
DR   TIGRFAMs; TIGR00327; secE_euk_arch; 1.
DR   PROSITE; PS01067; SECE_SEC61G; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..70
FT                   /note="Probable protein transport protein Sec61 subunit
FT                   gamma"
FT                   /id="PRO_0000104209"
FT   TOPO_DOM        1..39
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..70
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   70 AA;  7809 MW;  ED4EC64FE6B2E9BC CRC64;
     MADQIQEILD VPREFLKDGI QFIKKCQKPD RREFIKISQA VGTGFLIMGA VGYLVKLIHI
     PLNQVLVGGA