ID   SC61G_XENLA             Reviewed;          68 AA.
AC   Q66KU2;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Protein transport protein Sec61 subunit gamma;
GN   Name=sec61g;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC       reticulum and multi-pass membrane protein biogenesis.
CC       {ECO:0000250|UniProtKB:P60059}.
CC   -!- SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and
CC       SEC61-gamma (By similarity). Component of the ribosome-associated ER
CC       translocon complex (By similarity). {ECO:0000250|UniProtKB:P60058,
CC       ECO:0000250|UniProtKB:P60059}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:P60058}; Single-pass membrane protein
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC078558; AAH78558.1; -; mRNA.
DR   RefSeq; NP_001165129.1; NM_001171658.2.
DR   RefSeq; NP_001165130.1; NM_001171659.1.
DR   AlphaFoldDB; Q66KU2; -.
DR   SMR; Q66KU2; -.
DR   DNASU; 394424; -.
DR   GeneID; 100329133; -.
DR   GeneID; 394424; -.
DR   KEGG; xla:100329133; -.
DR   KEGG; xla:394424; -.
DR   CTD; 100329133; -.
DR   CTD; 394424; -.
DR   Xenbase; XB-GENE-865051; sec61g.L.
DR   Xenbase; XB-GENE-6464388; sec61g.S.
DR   OrthoDB; 1623399at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 100329133; Expressed in gastrula and 15 other tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
DR   Gene3D; 1.20.5.820; -; 1.
DR   HAMAP; MF_00422; SecE; 1.
DR   InterPro; IPR023391; Prot_translocase_SecE_dom_sf.
DR   InterPro; IPR008158; Translocase_Sec61-g.
DR   InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR   Pfam; PF00584; SecE; 1.
DR   SUPFAM; SSF103456; SSF103456; 1.
DR   TIGRFAMs; TIGR00327; secE_euk_arch; 1.
DR   PROSITE; PS01067; SECE_SEC61G; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..68
FT                   /note="Protein transport protein Sec61 subunit gamma"
FT                   /id="PRO_0000300688"
FT   TOPO_DOM        1..32
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        62..68
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   68 AA;  7771 MW;  0908279A22548561 CRC64;
     MDQVMQFVEP SRQFVKDSIR LVKRCTKPDR KEFQKIAMAT AIGFAIMGFI GFFVKLIHIP
     INNIIVGS