SCA1_RICCN
ID SCA1_RICCN Reviewed; 1902 AA.
AC Q92JP8; Q20DN5;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Putative surface cell antigen sca1;
DE Flags: Precursor;
GN Name=sca1; OrderedLocusNames=RC0019;
OS Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=272944;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-613 / Malish 7;
RX PubMed=11557893; DOI=10.1126/science.1061471;
RA Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL Science 293:2093-2098(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1629-1790, AND TRANSCRIPTION.
RC STRAIN=ATCC VR-613 / Malish 7;
RX PubMed=16504018; DOI=10.1186/1471-2180-6-12;
RA Ngwamidiba M., Blanc G., Raoult D., Fournier P.-E.;
RT "Sca1, a previously undescribed paralog from autotransporter protein-
RT encoding genes in Rickettsia species.";
RL BMC Microbiol. 6:12-12(2006).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE006914; AAL02557.1; -; Genomic_DNA.
DR EMBL; DQ306906; ABC41076.1; -; Genomic_DNA.
DR PIR; C97702; C97702.
DR RefSeq; WP_010976707.1; NC_003103.1.
DR AlphaFoldDB; Q92JP8; -.
DR EnsemblBacteria; AAL02557; AAL02557; RC0019.
DR KEGG; rco:RC0019; -.
DR PATRIC; fig|272944.4.peg.21; -.
DR HOGENOM; CLU_002510_0_0_5; -.
DR OMA; KTTYSYG; -.
DR Proteomes; UP000000816; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.128.130; -; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR Pfam; PF03797; Autotransporter; 1.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; SSF103515; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal; Transmembrane;
KW Transmembrane beta strand.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..1902
FT /note="Putative surface cell antigen sca1"
FT /id="PRO_0000259742"
FT DOMAIN 1618..1902
FT /note="Autotransporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00556"
FT REGION 140..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1470..1548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1488..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1506..1520
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1521..1542
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1902 AA; 212153 MW; F2D817457EF1912A CRC64;
MNKLTEQHLL KKSRFLKYSL LASISVGAAI PFEGMAMSKE AFRIDLSNKL LNHVSQLNGY
KDTTNNTPQQ IGKVIVSEPK INTYTPSEIR EMKISNKPKA SNPLKDVPIE DHYKVVARSK
SDVGTARKVR PITRCKTFAG IEKTEQSQNT YTPESTEQMP QKPEIIITAS SPTVSPASNS
FITAPNTPNT TLTSPEHYTT APGTPSSTPA TPYQSTSDSK PNDSLGANTP PNINTNSKAV
RRLSFSSSGP QQQAVQSSSQ VKSEVPPKPT FVPLPIKKSS TEIVAGMVSN ISRVNEMIGI
KLAEVTQAID TTDKKDKERL QKLYTQLTST QKTTEKLKSR AEEIETKIKI GENKDKIKKL
EKELTSKNNK ADRLFQKIEK IDIPANKVSI KSQETVPVTT ASTEVSAFQA QQARINEARQ
GVFNKNKSSG GNARKSSAGT KREKKKQEAQ KQLSEIKKQE KAIKTASDKA KEVAASAKKE
TSRTALRAMQ DKMNGDSEQL NKIEENLKLL TPVVYNSSTG PTYKQSPKAT PTIPLSHGVQ
RILGEQPEDE EGYLVPIKVQ QQPYQEIEDP IPSHSKDIYE AKVSQYINYL NSIQPNQSNQ
AQIDSVIDGL ATEMRKFSAD QFSQKLGEIA HLASIKAYEG LFEKLYEIQQ ARILETQKVY
EQAEISQSYA EYEENSRKSS IPVLSRSSSA KSVISSNFEE KSALLQTTTT DESLRSDNNW
KNSAPYSSSP KLDKRGLEYL DLAGDAFVQN LKQPDTLTIE TLGLITPTQN TTVAKSDSSR
KNNVSGSISE IQQLQSEKMR TETLGVQDDL GLDLHYTPQE TLTEKSTYLV SSKKKQGNII
KRAVSKVGSI LQTNYAENRR RKRDGETSKQ RTVDQEGEFG HAWGNENHKE SSLSVVSGCI
KKATQLISLL DAKRTAILQT TSPSQRRSVS LVLQEIENDY REAIKISQKL QQVLIRKPED
IKAYNAKAEK KLDAIKSRAD KHFNNIETDV DVGFNPNGGN SHSMPTANMD ILPKNLAVTP
PTNVGSLYNS PQAQQFQEDH KNIIINDRSQ GRLNLVDSTI VRELTDVDAS IYNTAPPEVL
KEAEALLDRS QGRLNLVDNT IKKGTQPLSN LSTIYESVSY ENLASETIYK TEQPKPSISY
TNTSKRKLPI PLFRSAELDK KLEYLDLEDK LLEVEEARIV KEKEAIAKLN QYQDPENLEF
KRLAMEALDL SSKESQLKQK RKAIEAEFSL NEKSSSTDVS ILRSYSIDDI SGVLSDAESN
LSRSPSVSGL EDLNNSNVMQ LEELKSKHEK IANDYNKELE LDTLNKEKIW LEGEIKHLDT
EFKPKVTESK PVFSCSSSVG SINSFSNDDD LSSRDVVTPV DTLNIEINKD YVDTYIRVLS
NKIQKIEEIQ KIEELSGSSS RSEELNHIKE AMAYISNRIQ DVEELDEKML LAINAQLQEH
DEKISSLLRE EATDILAQLL LQEMLVSDGK SESTLPAGDE EQEDTEVSRQ LSSLPALASS
NESALALSDD REKECLALGD SSEDEESYDS GFEEEEETIG QLSDSDGDNL KITEVDTVIP
LEQEAKKEMQ TQISENAPTL NQAKVVNTIV NNMIRNRLDA SMNMSNNMVA VGAGDEEESH
IKRGLWMRGM YGTNNHGRVE NMTGYRGTNK GATIGFDAEI DNNIVGIAYS NVHSVFKFKN
SKNNDKELIN SHVVSIYGQK ELPKNFALQA LVSASKNFIK DKTTYSYGDT KIKSNVKHRN
HSYNAEALLH YNYLLQSKLV ITPNIGLRYG KSRDGVYNET GVNVQEIALT MKENNILSGI
VGTKVTVPLK DALKFNNLGL IFQGAVEHNF KEKTQRINRV VKIFDNTFKH NYLIPKQPKT
SYNLGTGIIG SIKNTTISLD YNYYLNKHYR SHQGSVKLKV NL