ID   SCA4_RICFE              Reviewed;        1039 AA.
AC   Q9AJ37; Q4ULJ7;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 2.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Antigenic heat-stable 120 kDa protein;
DE   AltName: Full=120 kDa antigen;
DE   AltName: Full=Protein PS 120;
DE            Short=PS120;
GN   Name=sca4; Synonyms=D; OrderedLocusNames=RF_0725;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 53-1033.
RX   PubMed=11491333; DOI=10.1099/00207713-51-4-1353;
RA   Sekeyova Z., Roux V., Raoult D.;
RT   "Phylogeny of Rickettsia spp. inferred by comparing sequences of 'gene D',
RT   which encodes an intracytoplasmic protein.";
RL   Int. J. Syst. Evol. Microbiol. 51:1353-1360(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR   EMBL; CP000053; AAY61576.1; -; Genomic_DNA.
DR   EMBL; AF196973; AAK31304.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9AJ37; -.
DR   SMR; Q9AJ37; -.
DR   STRING; 315456.RF_0725; -.
DR   EnsemblBacteria; AAY61576; AAY61576; RF_0725.
DR   KEGG; rfe:RF_0725; -.
DR   eggNOG; COG5183; Bacteria.
DR   HOGENOM; CLU_009206_0_0_5; -.
DR   OMA; TAHYEEG; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR020954; Rickettsia_antigen_120kDa.
DR   Pfam; PF12574; 120_Rick_ant; 1.
PE   4: Predicted;
KW   Cytoplasm.
FT   CHAIN           1..1039
FT                   /note="Antigenic heat-stable 120 kDa protein"
FT                   /id="PRO_0000097611"
FT   REGION          1..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1020..1039
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..67
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..115
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        59..61
FT                   /note="QKQ -> EKH (in Ref. 2; AAK31304)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        447..450
FT                   /note="NAAT -> YATS (in Ref. 2; AAK31304)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        559
FT                   /note="L -> Q (in Ref. 2; AAK31304)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        930
FT                   /note="D -> V (in Ref. 2; AAK31304)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1039 AA;  113715 MW;  7820DCED2EE34AA4 CRC64;
     MSKDSDNPGY ESGYESDTEE KKQEQAVPAQ PISSTANKDG NPDTSEFDPL ANKEYTEEQK
     QKLEQEQKEY FSQTTPQELE ADDGFSFTPA SSTQSTPSIS SLSGGISSDS QTSDPITKAV
     RETIIQPQKD EIAEQILKDL AALADRDLAE QKRKEIEEEK DKTLSAFFGN PANREFIDKA
     LENPELKKKL ESIEIAGYKN VLSTYSAANG YQGGFKPVQW ENQISASDLR ATVVRNDAGD
     ELCTLNETTV KTKPFTVAKQ DGTQVQINSY REIDFPIKLD KADGSMHLSM VALKADGTKP
     SKDKAVYFTA HYEEGPNGKP QLKEISSPKP LKFAGDGPDA VAYIEHGGEI YTLAVTRGKY
     KEMMREVELN QGQSVDLSQT IAEDLTKVQG RSQETPQPII TPNQELKSSI ETPTTTQVPP
     ITPANQPLQP ETSQMPQPQQ VNPNLLNAAT ALSTSMQDLL NYVNAGLTKE KDGNKQIDLI
     NEAATAILNN EKSDIAEKQA NIIALTENTV NNNDLTPDTK VAGVNAVLET IKNDQNTPDL
     EKSKMLEATV AIALNSENLE PKQKQQMLEK AVDVGLSLKD DASRVTAIDG ITDAVIKSNL
     STEDKGTMLI AVGDKVNASE LSNAEKQKLL GSVLKKGVEA QVLSPEQQQL MQQNLDKITA
     EQTKNAQITE VQGILANPAF NTIAKTEAIQ NVTTKVLDSP IKAEIKGETL ESITKVVAES
     PLNGQDKADI VKGMGEAIAS HKTMAPTEKI STIESVEKGV AESITDLEDK KLMTKGLVEG
     IYEGKANPEI TSEKTKAVSR GIDKSTAIPE DKQALKDAAN EAALDRETQN LTEGLKRQNL
     GEPKPRDDIY NKAQDVADAL KNVITPVLDA HPEKREVSEE EEVVKKTSSI LNDISKLAIE
     KVNNFRAMLS PDGNLKTLEE KKAESTKKVD ELVKEFGTKS STEEQQSFIK ANLIDDKTLS
     KEIRLQTINK LLQEQAQKRA EAIENPNVKT EDVRVVSGVN IKDNIKIMGA LMNARDSIIQ
     SENLNKSTPI KRESSFPPR