ID   SCA4_RICJY              Reviewed;        1018 AA.
AC   Q9AJ79; G4KN65; O06654;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2001, sequence version 2.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Antigenic heat-stable 120 kDa protein;
DE   AltName: Full=120 kDa antigen;
DE   AltName: Full=Protein PS 120;
DE            Short=PS120;
DE            Short=rps120;
GN   Name=sca4; Synonyms=D; OrderedLocusNames=RJP_0510;
OS   Rickettsia japonica (strain ATCC VR-1363 / YH).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=652620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC VR-1363 / YH;
RX   PubMed=10585146; DOI=10.1111/j.1348-0421.1999.tb03360.x;
RA   Uchiyama T.;
RT   "Sequence analysis of the gene encoding a spotted fever group-specific
RT   intracytoplasmic protein PS120 of Rickettsia japonica.";
RL   Microbiol. Immunol. 43:983-987(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1363 / YH;
RX   PubMed=24039725; DOI=10.1371/journal.pone.0071861;
RA   Matsutani M., Ogawa M., Takaoka N., Hanaoka N., Toh H., Yamashita A.,
RA   Oshima K., Hirakawa H., Kuhara S., Suzuki H., Hattori M., Kishimoto T.,
RA   Ando S., Azuma Y., Shirai M.;
RT   "Complete genomic DNA sequence of the East Asian spotted fever disease
RT   agent Rickettsia japonica.";
RL   PLoS ONE 8:E71861-E71861(2013).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-1012.
RC   STRAIN=YM;
RX   PubMed=11491333; DOI=10.1099/00207713-51-4-1353;
RA   Sekeyova Z., Roux V., Raoult D.;
RT   "Phylogeny of Rickettsia spp. inferred by comparing sequences of 'gene D',
RT   which encodes an intracytoplasmic protein.";
RL   Int. J. Syst. Evol. Microbiol. 51:1353-1360(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAK96723.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB003696; BAA20142.1; -; Genomic_DNA.
DR   EMBL; AP011533; BAK96723.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AF155055; AAK30686.1; -; Genomic_DNA.
DR   PIR; T30853; T30853.
DR   AlphaFoldDB; Q9AJ79; -.
DR   SMR; Q9AJ79; -.
DR   EnsemblBacteria; BAK96723; BAK96723; RJP_0510.
DR   KEGG; rja:RJP_0510; -.
DR   HOGENOM; CLU_009206_0_0_5; -.
DR   Proteomes; UP000002659; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR020954; Rickettsia_antigen_120kDa.
DR   Pfam; PF12574; 120_Rick_ant; 1.
PE   4: Predicted;
KW   Cytoplasm.
FT   CHAIN           1..1018
FT                   /note="Antigenic heat-stable 120 kDa protein"
FT                   /id="PRO_0000097612"
FT   REGION          1..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..402
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          995..1018
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        8
FT                   /note="N -> D (in Ref. 3; AAK30686)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        449
FT                   /note="K -> E (in Ref. 3; AAK30686)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        693
FT                   /note="S -> G (in Ref. 3; AAK30686)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1018 AA;  111148 MW;  F41F015392671BAA CRC64;
     MSKDGNLNTS EFDPLANKEY TEEQKQTLEQ EQKEFLSQTT TPELEADDGF IVTSASSAQS
     TPSTSALSGN ISPDSQTSDP ITKAVRETII QPQKDNLIEQ ILKDLAALTD HDLAEQKRKE
     IEEEKDKDKT LSTFFGNPAN REFIDKALEN PELKKKLESI EIAGYKNVHN TFSAASGYPG
     GFKPVQWENH VSASDLRATV VKNDAGDELC TLNETTVKTK PFTLAKQDGT QVQISSYREI
     DFPIKLDKAD GSMHLSMVAL KADGTKPSKD KAVYFTAHYE EGPNGKPQLK EISSPKPLKF
     AGTGDDAIAY IEHGGEIYTL AVTRGKYKEM MKEVELNQGQ SVDLSQAEDI IIGQGQSKEQ
     PLITPQQTTS SSVEPPQYKQ QVPPITPTNQ PLQPETSQMP QSQQVNPNLL NAATALSGSM
     QDLLNYVNAG LTKEIDLIKE AATAILNDKK SDIAEKQANI IALAENTVNN KNLTPDAKVA
     GVNAVLETIK NDQNTPDLEK SKMLEATVAI ALNSENLEPK QKQQILEKAV DVGLSLKDDA
     SRAAAIDGIT DAVIKSNLST EDKGTMFIAV GDKVNVSELS NAEKQKLLGS VLKKGVEAQV
     LSPAQQQLMQ QNLDKITAEQ TKKDTIKKVN DILFDPLSNT ELKTTNIQAI ISNVLDGPAT
     AEVKGEIIQE ITNTVAGSSL EAHDKAAIIK GISETIATHS DTSLSLPNKA LIMASAEKGI
     AESQANLPDR ELMTKGLVDG IYEGKGGPEI TKAVSSGIDN SNINDSEKEA LKKAKDAASE
     AALDRETQNL TEGLKGQNIE EHKPHDDIYN KVREVINAVN PVIEALEKSK EPVVSAEERI
     VQETSSILNN ISKLAVEKVN NFRAMLSPNG NLKTLEEKKE ESIKKVDELV KAFGTKSSTE
     EQQSFIKANL IDDKTLSKEI RLQTIDKLLQ EQKRAEAIEN PSVKTEDVRV VSGKSKLKPI
     SKDKPDIEKA KMVVGRDRVN IKGNIKIMRA LMNARDSIQS ENLNKSTPIK RESSPPQR