ID   SCA4_RICPR              Reviewed;        1022 AA.
AC   Q9ZD49; Q9AJ36; Q9ZD48;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2001, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Antigenic heat-stable 120 kDa protein;
DE   AltName: Full=120 kDa antigen;
DE   AltName: Full=Protein PS 120;
DE            Short=PS120;
GN   Name=sca4; OrderedLocusNames=RP498/RP499;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 11-1016.
RX   PubMed=11491333; DOI=10.1099/00207713-51-4-1353;
RA   Sekeyova Z., Roux V., Raoult D.;
RT   "Phylogeny of Rickettsia spp. inferred by comparing sequences of 'gene D',
RT   which encodes an intracytoplasmic protein.";
RL   Int. J. Syst. Evol. Microbiol. 51:1353-1360(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA14950.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AJ235272; CAA14951.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AJ235272; CAA14950.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AF200340; AAK31305.1; -; Genomic_DNA.
DR   PIR; D71653; D71653.
DR   PIR; E71653; E71653.
DR   RefSeq; NP_220874.1; NC_000963.1.
DR   RefSeq; NP_220875.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZD49; -.
DR   SMR; Q9ZD49; -.
DR   STRING; 272947.RP498; -.
DR   EnsemblBacteria; CAA14950; CAA14950; CAA14950.
DR   EnsemblBacteria; CAA14951; CAA14951; CAA14951.
DR   KEGG; rpr:RP498; -.
DR   KEGG; rpr:RP499; -.
DR   PATRIC; fig|272947.5.peg.507; -.
DR   eggNOG; COG5183; Bacteria.
DR   HOGENOM; CLU_009206_0_0_5; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR020954; Rickettsia_antigen_120kDa.
DR   Pfam; PF12574; 120_Rick_ant; 1.
PE   4: Predicted;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..1022
FT                   /note="Antigenic heat-stable 120 kDa protein"
FT                   /id="PRO_0000097615"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        11..15
FT                   /note="EFDPL -> RPGLV (in Ref. 2; AAK31305)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        365
FT                   /note="H -> Y (in Ref. 2; AAK31305)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        413
FT                   /note="Missing (in Ref. 2; AAK31305)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        957
FT                   /note="G -> R (in Ref. 2; AAK31305)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1022 AA;  114410 MW;  03230E3A663A9622 CRC64;
     MSKNGNQDIS EFDPLNREFT EAEKQQQMQQ EQEFFSQTIL DIADDGFMVA SSSQATPSIS
     FLSNNRPHGD HKSDPITEAI RKEILEKQRD ILREYFVNTN PELAEQIAKE EDDRKFRAFL
     SNQDNYALIN KAFEDTKTKK NLEKAEIVGY KNVLSTYSVA NGYQGGFQPV QWENQVSASD
     LRSTVVKNDE GEELCTLNET TVKTKDLIVA KQDGTQVQIN SYREINFPIK LDKANGSMHL
     SMVALKADGT KPAKDKAVYF TAHYEEGPNG KPQLKEISSP QPLKFVGTGD DAVAYIEHGG
     EIYTLAVTRG KYKEMMKEVA LNHGQSVALS QTIAEDLTHV QGPSHETHKP IIIPNQELES
     SIEQHTSQQV PPITTFNKSL QPKISQIHQL QPQQAQSSGI PNPVLNAANA LSTSMQDLLN
     NINSYLTKNQ DINKQSDLIK EAAIAILNNK KSDFAEKQYN IIDLAKNIFS NKDIIADAKV
     NVVNTLLETI QNDQNTLDIK KSKILEDTVA ITLNSENIEL KQKQQILEKV VDIGLSIKDD
     ISRVVAVDSI MDTVIKSNIA NEDKEKIFIT VFDQINSYEF SNVAKQKLLD SILKKTAETQ
     VLSPEQQQLM NQNLDNITTE HTKRDTIEKV NNILLEPLSN TALKTTNIQV MTSNVLDSPV
     QIEMKSKLIQ VVTKTVAESA LVEPKDKTEI VKGIGKTIVT HSDTSLPLHD KVVIMGSVAK
     GIVESKNDLL DRELIIAGLV DGIYEAKGDN AVVHAISSMI ANSNINQSEK EALKRSQDVV
     SEKVLDKEIQ NLDRELKAQN INESKLHDDI YNKTQDVANA LKNVITTVLD DNSGQRGVSE
     EAPKKVSSLL NDISKRTIEK INNLRAMLSQ DGNLKTFEEK KDEATKKVDE LVKAFDNKSS
     TEEQQNFIKS NLIDNKTLSR EIRLQIIDNL LKAQAQKRAE TIENLSAKTE DVRVISGKSE
     LKPISQDEPY IQKAKMVVER DRVDIKDNIK IMSALINARD SIQSENFNKS IHIKKESSFP
     QR