ID   SCAB2_ARATH             Reviewed;         492 AA.
AC   F4IIZ9; O22196;
DT   04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Stomatal closure-related actin-binding protein 2 {ECO:0000303|PubMed:21719691};
GN   Name=SCAB2 {ECO:0000303|PubMed:21719691};
GN   OrderedLocusNames=At2g40820 {ECO:0000312|Araport:AT2G40820};
GN   ORFNames=T20B5.2 {ECO:0000312|EMBL:AAB86442.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   FUNCTION, GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=21719691; DOI=10.1105/tpc.111.086546;
RA   Zhao Y., Zhao S., Mao T., Qu X., Cao W., Zhang L., Zhang W., He L., Li S.,
RA   Ren S., Zhao J., Zhu G., Huang S., Ye K., Yuan M., Guo Y.;
RT   "The plant-specific actin binding protein SCAB1 stabilizes actin filaments
RT   and regulates stomatal movement in Arabidopsis.";
RL   Plant Cell 23:2314-2330(2011).
CC   -!- FUNCTION: Probable plant-specific actin binding protein that bundles
CC       and stabilizes microfilaments (MFs). {ECO:0000303|PubMed:21719691}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:O48791}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, siliques and
CC       flowers. {ECO:0000303|PubMed:21719691}.
CC   -!- SIMILARITY: Belongs to the SCAB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB86442.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC002409; AAB86442.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC09885.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61778.1; -; Genomic_DNA.
DR   PIR; T00746; T00746.
DR   RefSeq; NP_001323977.1; NM_001336868.1.
DR   RefSeq; NP_181614.7; NM_129645.9.
DR   AlphaFoldDB; F4IIZ9; -.
DR   SMR; F4IIZ9; -.
DR   STRING; 3702.AT2G40820.1; -.
DR   iPTMnet; F4IIZ9; -.
DR   PaxDb; F4IIZ9; -.
DR   ProteomicsDB; 232903; -.
DR   EnsemblPlants; AT2G40820.1; AT2G40820.1; AT2G40820.
DR   EnsemblPlants; AT2G40820.2; AT2G40820.2; AT2G40820.
DR   GeneID; 818679; -.
DR   Gramene; AT2G40820.1; AT2G40820.1; AT2G40820.
DR   Gramene; AT2G40820.2; AT2G40820.2; AT2G40820.
DR   KEGG; ath:AT2G40820; -.
DR   Araport; AT2G40820; -.
DR   TAIR; locus:2058455; AT2G40820.
DR   eggNOG; ENOG502QRDW; Eukaryota.
DR   HOGENOM; CLU_026412_2_0_1; -.
DR   InParanoid; F4IIZ9; -.
DR   PRO; PR:F4IIZ9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; F4IIZ9; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   GO; GO:0010119; P:regulation of stomatal movement; IEA:InterPro.
DR   InterPro; IPR039640; SCAB.
DR   InterPro; IPR032012; SCAB-ABD.
DR   InterPro; IPR041144; SCAB-PH.
DR   InterPro; IPR032009; SCAB_CC.
DR   PANTHER; PTHR31172; PTHR31172; 1.
DR   Pfam; PF16711; SCAB-ABD; 1.
DR   Pfam; PF17684; SCAB-PH; 1.
DR   Pfam; PF16712; SCAB_CC; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding; Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..492
FT                   /note="Stomatal closure-related actin-binding protein 2"
FT                   /id="PRO_0000431808"
FT   COILED          112..132
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   492 AA;  54434 MW;  9B38FD21E0F22043 CRC64;
     MTKVCPKTEE KRVVSEAVVE PISADVSFAS NHFPTYKLGP DDQIVDEPDE DDKVPSVKDV
     VGKETGDLSD QHKKLSVRDL ACKFDKNLAA ASKLVDEAKL NDVTSLEGHV MLKKLRDALE
     TMRGRMDGRN REAVEKAISM VEALAVKLTQ NEGELIHDKF EVKKLASFLK KASDDAKKLV
     NQEKSFACAE IESARALVMK LGGAFEEQEL CSKASRDQGP NVEKLVEEVQ EARRIRRLHK
     PTMVIGMQHE LRDLKSQIQE KSAYSVKLQR EIAIIKKAEG SKSCPYVLDG AQSLGSCLRI
     RASSDSGIDI SKCSIHWYRA ASESSRREAI SGANRSVYAP EPFDVGRVIQ ADIVSNGQKF
     TVTTDGPINT AAGLQSRVES LLRKSNSEFT VVISQMNGQD HASRSHVFTV GKARIKLSRG
     WITKAREIYS TSMQLCGVRG NANVPAKALF WQLRKGLTFL LTFESEQERN AAIVLARTYA
     YDCNVTLVGP DD