SCAM1_ARATH
ID SCAM1_ARATH Reviewed; 282 AA.
AC Q9SKT3;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Secretory carrier-associated membrane protein 1;
DE Short=AtSC1;
DE Short=Secretory carrier membrane protein 1;
GN Name=SCAMP1; Synonyms=SC1; OrderedLocusNames=At2g20840; ORFNames=F5H14.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10982391; DOI=10.1091/mbc.11.9.2933;
RA Hubbard C., Singleton D., Rauch M., Jayasinghe S., Cafiso D., Castle D.;
RT "The secretory carrier membrane protein family: structure and membrane
RT topology.";
RL Mol. Biol. Cell 11:2933-2947(2000).
CC -!- FUNCTION: Probably involved in membrane trafficking. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane
CC {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SCAMP family. {ECO:0000305}.
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DR EMBL; AC006234; AAD20911.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07086.1; -; Genomic_DNA.
DR EMBL; BT012642; AAT06461.1; -; mRNA.
DR EMBL; AK221723; BAD93720.1; -; mRNA.
DR PIR; A84594; A84594.
DR RefSeq; NP_179680.1; NM_127653.5.
DR AlphaFoldDB; Q9SKT3; -.
DR SMR; Q9SKT3; -.
DR STRING; 3702.AT2G20840.1; -.
DR TCDB; 8.A.103.1.6; the secretory carrier-associated membrane protein (scamp) family.
DR iPTMnet; Q9SKT3; -.
DR PaxDb; Q9SKT3; -.
DR PRIDE; Q9SKT3; -.
DR ProteomicsDB; 232768; -.
DR EnsemblPlants; AT2G20840.1; AT2G20840.1; AT2G20840.
DR GeneID; 816617; -.
DR Gramene; AT2G20840.1; AT2G20840.1; AT2G20840.
DR KEGG; ath:AT2G20840; -.
DR Araport; AT2G20840; -.
DR TAIR; locus:2051409; AT2G20840.
DR eggNOG; KOG3088; Eukaryota.
DR HOGENOM; CLU_066546_3_0_1; -.
DR InParanoid; Q9SKT3; -.
DR OMA; RPSTHYA; -.
DR OrthoDB; 995882at2759; -.
DR PhylomeDB; Q9SKT3; -.
DR PRO; PR:Q9SKT3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SKT3; baseline and differential.
DR Genevisible; Q9SKT3; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0055038; C:recycling endosome membrane; IBA:GO_Central.
DR GO; GO:0032588; C:trans-Golgi network membrane; IBA:GO_Central.
DR GO; GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR InterPro; IPR007273; SCAMP.
DR PANTHER; PTHR10687; PTHR10687; 1.
DR Pfam; PF04144; SCAMP; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Coiled coil; Cytoplasmic vesicle; Membrane; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..282
FT /note="Secretory carrier-associated membrane protein 1"
FT /id="PRO_0000304900"
FT TOPO_DOM 1..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 254..282
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 48..93
FT /evidence="ECO:0000255"
FT MOD_RES 31
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9M5P2"
SQ SEQUENCE 282 AA; 31963 MW; B70E2192CE94BA31 CRC64;
MSRYQSHSFD DGEINPFANP TSVPAATSKL SPLPPEPYDR GATMDIPLDS GKDLKAKEKE
LREKEAELKR REQEIKRKED AIAQAGIVIE EKNWPPFFPL IHHDISNEIP IHLQRIQYVA
FTSMLGLVVC LLWNIVAVTT AWIKGEGPTI WFLAIIYFIS GVPGAYVMWY RPLYRAMRTD
SALKFGWFFF TYLFHIAFCV FAAVAPPIIF KGKSLTGILP AIDVLSGNIL VGIFYFIGFG
FFCLESLVSI WVIQQVYMYF RGSGKAAEMK QEATRRAMMA AL
