ID   SCAM4_RAT               Reviewed;         230 AA.
AC   Q9ET20;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Secretory carrier-associated membrane protein 4;
DE            Short=SCAMP-4;
DE            Short=Secretory carrier membrane protein 4;
GN   Name=Scamp4;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain;
RX   PubMed=11295240; DOI=10.1016/s0169-328x(01)00043-2;
RA   Krebs C.J., Pfaff D.W.;
RT   "Expression of the SCAMP-4 gene, a new member of the secretory carrier
RT   membrane protein family, is repressed by progesterone in brain regions
RT   associated with female sexual behavior.";
RL   Brain Res. Mol. Brain Res. 88:144-154(2001).
CC   -!- FUNCTION: Probably involved in membrane protein trafficking.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the SCAMP family. {ECO:0000305}.
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DR   EMBL; AF285631; AAG00522.1; -; mRNA.
DR   RefSeq; NP_113913.1; NM_031725.1.
DR   AlphaFoldDB; Q9ET20; -.
DR   STRING; 10116.ENSRNOP00000024980; -.
DR   jPOST; Q9ET20; -.
DR   PaxDb; Q9ET20; -.
DR   GeneID; 65170; -.
DR   KEGG; rno:65170; -.
DR   UCSC; RGD:68354; rat.
DR   CTD; 113178; -.
DR   RGD; 68354; Scamp4.
DR   eggNOG; KOG3088; Eukaryota.
DR   InParanoid; Q9ET20; -.
DR   PhylomeDB; Q9ET20; -.
DR   PRO; PR:Q9ET20; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055038; C:recycling endosome membrane; IBA:GO_Central.
DR   GO; GO:0032588; C:trans-Golgi network membrane; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IDA:RGD.
DR   GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR   GO; GO:0019098; P:reproductive behavior; NAS:RGD.
DR   InterPro; IPR007273; SCAMP.
DR   PANTHER; PTHR10687; PTHR10687; 1.
DR   Pfam; PF04144; SCAMP; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Phosphoprotein; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..230
FT                   /note="Secretory carrier-associated membrane protein 4"
FT                   /id="PRO_0000191261"
FT   TOPO_DOM        1..39
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        170..230
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          197..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         194
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q969E2"
SQ   SEQUENCE   230 AA;  25512 MW;  304B4A6045D5AC98 CRC64;
     MAGKENNFPP LPHFLPLKPC FYQDFSDEIP VEHQVLVKRI YRLWMFYCTT LGVNLVACLA
     WWIAGGAGAN FGLAMLWLVL FTPCSYVCWF RPAYKAFRAD SSFNFMAFFF IFGAQFVLTV
     IQAIGFSGWG ACGWLATIGF FGTSVGAAVV MLIPAIMFSL SAVVMAITIV KVHRIYRGAG
     GSLQKAQTEW SAGTWRNPPS REAQFNSFSG NSLPEYPTVP SYSTSGSQWP