ID   SCCT_CHLAA              Reviewed;         402 AA.
AC   A9WGE3;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Succinyl-CoA--D-citramalate CoA-transferase;
DE            EC=2.8.3.20;
GN   OrderedLocusNames=Caur_2266;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Involved in the 3-hydroxypropionate cycle used for
CC       autotrophic carbon dioxide fixation, and in the glyoxylate assimilation
CC       cycle used to regenerate acetyl-CoA and produce pyruvate as universal
CC       precursor for biosynthesis. Catalyzes the transfer of CoA moiety from
CC       succinyl-CoA to D-citramalate to yield citramalyl-CoA (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(3R)-citramalate + succinyl-CoA = (3R)-citramalyl-CoA +
CC         succinate; Xref=Rhea:RHEA:38279, ChEBI:CHEBI:30031,
CC         ChEBI:CHEBI:30934, ChEBI:CHEBI:57292, ChEBI:CHEBI:75637; EC=2.8.3.20;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-malate + succinyl-CoA = (R)-malyl-CoA + succinate;
CC         Xref=Rhea:RHEA:40655, ChEBI:CHEBI:15588, ChEBI:CHEBI:30031,
CC         ChEBI:CHEBI:57292, ChEBI:CHEBI:77427; EC=2.8.3.20;
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- INDUCTION: Under autotrophic growth conditions. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CoA-transferase III family. {ECO:0000305}.
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DR   EMBL; CP000909; ABY35475.1; -; Genomic_DNA.
DR   RefSeq; WP_012258129.1; NC_010175.1.
DR   RefSeq; YP_001635864.1; NC_010175.1.
DR   AlphaFoldDB; A9WGE3; -.
DR   SMR; A9WGE3; -.
DR   STRING; 324602.Caur_2266; -.
DR   EnsemblBacteria; ABY35475; ABY35475; Caur_2266.
DR   KEGG; cau:Caur_2266; -.
DR   PATRIC; fig|324602.8.peg.2567; -.
DR   eggNOG; COG1804; Bacteria.
DR   HOGENOM; CLU_033975_0_0_0; -.
DR   InParanoid; A9WGE3; -.
DR   OMA; ERTGNIM; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0008410; F:CoA-transferase activity; ISS:UniProtKB.
DR   GO; GO:0043961; F:succinyl-CoA:(R)-citramalate CoA-transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043427; P:carbon fixation by 3-hydroxypropionate cycle; ISS:UniProtKB.
DR   Gene3D; 3.30.1540.10; -; 1.
DR   Gene3D; 3.40.50.10540; -; 1.
DR   InterPro; IPR003673; CoA-Trfase_fam_III.
DR   InterPro; IPR044855; CoA-Trfase_III_dom3_sf.
DR   InterPro; IPR023606; CoA-Trfase_III_dom_1_sf.
DR   Pfam; PF02515; CoA_transf_3; 1.
DR   SUPFAM; SSF89796; SSF89796; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transferase.
FT   CHAIN           1..402
FT                   /note="Succinyl-CoA--D-citramalate CoA-transferase"
FT                   /id="PRO_0000429590"
FT   ACT_SITE        174
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   402 AA;  44033 MW;  A70EFD8C667DE883 CRC64;
     MSSQRPPRPL DDVRVLELGA FLAGPFCGQL LADFGAEVIK VEPPGKGDPM REWGRHRYKG
     RTLWWPVLAR NKKSITIDLR TPEGQALVKR LVPHVDMVLE NFRPGTLEEW GLGWEELHAL
     NPGLIMIRVS GFGQTGPYRD KAGFGSIGEA MGGIRAITGF PDRPPTRIGI SIGDSLAATF
     AALGALVALH QRQRSGQGQV VDIGIYEGVL ALMESMIPEY QLTGHIRERT GNILPNVAPS
     NIYPTADGSW FVIGANADTI FTRLAQAMGQ PELATDPRFA THQARGEHQA ELDDLIAAWT
     LNYTADQLQV MMDEYGVPAG RIYTAKEMLS DPHFIARQSI IGVHDPDLGE IKMQNVVPRL
     SATPGGVDWT GPALGQHNRE IFTDLLGLTE DDLAMLQAKR VI