ID   SCDA_STAAB              Reviewed;         224 AA.
AC   Q2YV69;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Iron-sulfur cluster repair protein ScdA {ECO:0000255|HAMAP-Rule:MF_01156};
GN   Name=scdA {ECO:0000255|HAMAP-Rule:MF_01156}; OrderedLocusNames=SAB0198;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC       sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC       {ECO:0000255|HAMAP-Rule:MF_01156}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01156}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01156}.
CC   -!- SIMILARITY: Belongs to the RIC family. ScdA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01156}.
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DR   EMBL; AJ938182; CAI79886.1; -; Genomic_DNA.
DR   RefSeq; WP_000608825.1; NC_007622.1.
DR   AlphaFoldDB; Q2YV69; -.
DR   SMR; Q2YV69; -.
DR   KEGG; sab:SAB0198; -.
DR   HOGENOM; CLU_076075_0_1_9; -.
DR   OMA; ACTTWRV; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3910.10; -; 1.
DR   HAMAP; MF_01156; RIC_ScdA; 1.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR019903; RIC_family.
DR   InterPro; IPR023551; ScdA.
DR   InterPro; IPR038062; ScdA-like_N_sf.
DR   PANTHER; PTHR36438; PTHR36438; 1.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   Pfam; PF04405; ScdA_N; 1.
DR   SUPFAM; SSF140683; SSF140683; 1.
DR   TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Iron; Metal-binding; Stress response.
FT   CHAIN           1..224
FT                   /note="Iron-sulfur cluster repair protein ScdA"
FT                   /id="PRO_1000065536"
SQ   SEQUENCE   224 AA;  25468 MW;  E72F6E197AAA36FB CRC64;
     MINKNDIVAD VVTDYPKAAD IFRSVGIDFC CGGQISIEAA SLEKKNVDLN ELLQRLNDIE
     QTNTPGSLNP KFLNVSSLIQ YIQAAYHEPL REEFKNLTPY VTKLSKVHGP NHPYLVELKE
     TYDTFKNGML EHMQKEDDVD FPKLIKYEQG EVVDDINTVI DDLVSDHIAT GQLLVKMSDL
     TSSYEPPIVA CGTWRLVYQR LKALEVLTHE HVHLENHVLF KKVS