SCDA_STALH
ID SCDA_STALH Reviewed; 225 AA.
AC D3QFZ3;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 20-APR-2010, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Iron-sulfur cluster repair protein ScdA {ECO:0000255|HAMAP-Rule:MF_01156};
GN Name=scdA {ECO:0000255|HAMAP-Rule:MF_01156}; OrderedLocusNames=SLGD_02311;
OS Staphylococcus lugdunensis (strain HKU09-01).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=698737;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HKU09-01;
RX PubMed=20047907; DOI=10.1128/jb.01627-09;
RA Tse H., Tsoi H.W., Leung S.P., Lau S.K., Woo P.C., Yuen K.Y.;
RT "Complete genome sequence of Staphylococcus lugdunensis strain HKU09-01.";
RL J. Bacteriol. 192:1471-1472(2010).
CC -!- FUNCTION: Di-iron-containing protein involved in the repair of iron-
CC sulfur clusters damaged by oxidative and nitrosative stress conditions.
CC {ECO:0000255|HAMAP-Rule:MF_01156}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01156}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01156}.
CC -!- SIMILARITY: Belongs to the RIC family. ScdA subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01156}.
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DR EMBL; CP001837; ADC88398.1; -; Genomic_DNA.
DR RefSeq; WP_002479441.1; NC_013893.1.
DR AlphaFoldDB; D3QFZ3; -.
DR SMR; D3QFZ3; -.
DR KEGG; slg:SLGD_02311; -.
DR HOGENOM; CLU_076075_0_1_9; -.
DR OMA; ACTTWRV; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030091; P:protein repair; IEA:UniProtKB-UniRule.
DR GO; GO:0051409; P:response to nitrosative stress; IEA:UniProtKB-UniRule.
DR GO; GO:0006979; P:response to oxidative stress; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.3910.10; -; 1.
DR HAMAP; MF_01156; RIC_ScdA; 1.
DR InterPro; IPR012312; Hemerythrin-like.
DR InterPro; IPR019903; RIC_family.
DR InterPro; IPR023551; ScdA.
DR InterPro; IPR038062; ScdA-like_N_sf.
DR PANTHER; PTHR36438; PTHR36438; 1.
DR Pfam; PF01814; Hemerythrin; 1.
DR Pfam; PF04405; ScdA_N; 1.
DR SUPFAM; SSF140683; SSF140683; 1.
DR TIGRFAMs; TIGR03652; FeS_repair_RIC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Iron; Metal-binding; Stress response.
FT CHAIN 1..225
FT /note="Iron-sulfur cluster repair protein ScdA"
FT /id="PRO_0000406192"
SQ SEQUENCE 225 AA; 25559 MW; E3C815F558226038 CRC64;
MITKETIVAE VVTDYPKAAD VFKHAGIDFC CGGAISIEQA SQKSKLSLEA LLSQLQQLER
QSEPGGGLNP KYLSVASLIQ YIQAAYHEPL KEELKQLTPY ITKVAKVHGP QHDYLIELKA
LYTQYKNNMT AHTAQEDDHD FPKMIAFSNG QDVAEIEQII LDLKTDHDEV GQILKKMNQL
TNDYTIPNEA CNTWRLVYQR LQAIEKATYR HVHLENHVLF NKLHA