ID   SCED_STACT              Reviewed;         232 AA.
AC   O54493; B9DMG2;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Probable transglycosylase SceD;
DE            EC=3.2.-.-;
DE   Flags: Precursor;
GN   Name=sceD; OrderedLocusNames=Sca_1599;
OS   Staphylococcus carnosus (strain TM300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=396513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Krismer B., Goetz F.;
RT   "Identification of an operon involved in thiamin biosynthesis in
RT   Staphylococcus carnosus TM300.";
RL   Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM300;
RX   PubMed=19060169; DOI=10.1128/aem.01982-08;
RA   Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C.,
RA   Goetz F.;
RT   "Genome analysis of the meat starter culture bacterium Staphylococcus
RT   carnosus TM300.";
RL   Appl. Environ. Microbiol. 75:811-822(2009).
CC   -!- FUNCTION: Is able to cleave peptidoglycan and affects clumping and
CC       separation of bacterial cells. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the transglycosylase family. SceD subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AF109218; AAB94657.1; -; Genomic_DNA.
DR   EMBL; AM295250; CAL28505.1; -; Genomic_DNA.
DR   RefSeq; WP_015900845.1; NC_012121.1.
DR   AlphaFoldDB; O54493; -.
DR   SMR; O54493; -.
DR   STRING; 396513.SCA_1599; -.
DR   GeneID; 60544689; -.
DR   KEGG; sca:SCA_1599; -.
DR   eggNOG; COG1388; Bacteria.
DR   HOGENOM; CLU_099865_0_0_9; -.
DR   OMA; AGPSQWV; -.
DR   OrthoDB; 1172354at2; -.
DR   BioCyc; SCAR396513:SCA_RS08120-MON; -.
DR   Proteomes; UP000000444; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd13925; RPF; 1.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR010618; RPF.
DR   Pfam; PF06737; Transglycosylas; 1.
DR   SUPFAM; SSF53955; SSF53955; 1.
PE   3: Inferred from homology;
KW   Glycosidase; Hydrolase; Secreted; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..232
FT                   /note="Probable transglycosylase SceD"
FT                   /id="PRO_5000055436"
FT   REGION          84..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   232 AA;  24319 MW;  F441E33F4EEE1225 CRC64;
     MKKLLVASSA SAALFAVGVG ANAHAAEDNN VNQDQLAQTA LNNTQQLNDA PVQEGAYNIA
     FDNSGYNFNF NSDGTNWSWS YNADSSAQQA PAQSTTQEQA PAAQQAPAQS TTQEQAPAAQ
     QAPAQEQTQQ PAQQPAQQQT QQPAQQSADS GSNVQVNDHL KAIAQRESGG DIHAINSSSG
     AAGKYQFLQT TWDSVAPAEY QGKPASEAPE AVQDAAAQKL YDTAGPSQWV TA