ID   SCI1B_TOBAC             Reviewed;         158 AA.
AC   A0A1S3XQD6; F8QMT1;
DT   20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2018, sequence version 2.
DT   25-MAY-2022, entry version 15.
DE   RecName: Full=Style cell-cycle inhibitor 1-B {ECO:0000303|PubMed:21388377};
DE            Short=NtSCI1 {ECO:0000303|PubMed:21388377};
GN   Name=SCI1B {ECO:0000303|PubMed:21388377};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90;
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-147, FUNCTION, DISRUPTION PHENOTYPE,
RP   SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX   PubMed=21388377; DOI=10.1111/j.1469-8137.2011.03660.x;
RA   Depaoli H.C., Brito M.S., Quiapim A.C., Teixeira S.P., Goldman G.H.,
RA   Dornelas M.C., Goldman M.-H.S.;
RT   "Stigma/style cell cycle inhibitor 1 (SCI1), a tissue-specific cell cycle
RT   regulator that controls upper pistil development.";
RL   New Phytol. 190:882-895(2011).
RN   [3]
RP   FUNCTION.
RX   PubMed=22301969; DOI=10.4161/psb.7.1.18525;
RA   DePaoli H.C., Goldman G.H., Goldman M.-H.S.;
RT   "SCI1, the first member of the tissue-specific inhibitors of CDK (TIC)
RT   class, is probably connected to the auxin signaling pathway.";
RL   Plant Signal. Behav. 7:53-58(2012).
CC   -!- FUNCTION: Component of the auxin signaling transduction pathway that
CC       regulates cell proliferation and differentiation during flowers stigmas
CC       and styles development (PubMed:21388377). Involved in the regulation of
CC       auxin-related genes (PubMed:22301969). {ECO:0000269|PubMed:21388377,
CC       ECO:0000269|PubMed:22301969}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21388377}.
CC       Note=Inside the nucleus, confined to the interchromatic region.
CC       {ECO:0000269|PubMed:21388377}.
CC   -!- TISSUE SPECIFICITY: Specifically expressed in flowers pistils,
CC       especially in stigmas and styles. Barely detected in roots, stems,
CC       leaves, sepals, petals and stamen. {ECO:0000269|PubMed:21388377}.
CC   -!- DEVELOPMENTAL STAGE: Expressed at high levels at the early stages of
CC       pistil development (stages 1 to 6) and disappears towards anthesis
CC       (stages 7 to 12). At stage 4, observed in the stigmatic secretory zone,
CC       including the papillar cells, and in the stylar transmitting tissue.
CC       Expressed in stigma and style specialized tissues at initial stages of
CC       flower development. {ECO:0000269|PubMed:21388377}.
CC   -!- DISRUPTION PHENOTYPE: Enlarged stigmas and styles due to increased in
CC       cell numbers. {ECO:0000269|PubMed:21388377}.
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DR   EMBL; GQ272330; ADG60254.1; -; mRNA.
DR   AlphaFoldDB; A0A1S3XQD6; -.
DR   OrthoDB; 1564723at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0051782; P:negative regulation of cell division; IMP:UniProtKB.
DR   GO; GO:0010928; P:regulation of auxin mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0048480; P:stigma development; IMP:UniProtKB.
DR   GO; GO:0048479; P:style development; IMP:UniProtKB.
DR   InterPro; IPR044688; SCI-1-like.
DR   PANTHER; PTHR34117; PTHR34117; 1.
PE   2: Evidence at transcript level;
KW   Auxin signaling pathway; Developmental protein; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..158
FT                   /note="Style cell-cycle inhibitor 1-B"
FT                   /id="PRO_0000444451"
FT   REGION          1..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..44
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   158 AA;  18662 MW;  5365039EF9B5F14C CRC64;
     MGSDKKTTEE KRKHKRNSPS SPRDEVKSKR QNIKGDEERR KEKDKSKKEK HKSHKSKCHS
     SEEKKSGEKH KTKSHKHKDK SKNKFEELSK DDYFSKNNEF ASWLKDKKNL FFSDLSSETA
     RNLFSDFVIQ WNKGKLDSQY YEGIATGPRS SHAWNIKK