ID   SCK3_LEIQU              Reviewed;          14 AA.
AC   P45661;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   23-FEB-2022, entry version 54.
DE   RecName: Full=Leiurutoxin-3;
DE   AltName: Full=Leiurutoxin III;
DE   Flags: Fragment;
OS   Leiurus quinquestriatus quinquestriatus (Egyptian scorpion) (Deathstalker
OS   scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Leiurus.
OX   NCBI_TaxID=6885;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Venom;
RX   PubMed=1280139;
RA   Valdivia H.H., Martin B.M., Escobar L., Possani L.D.;
RT   "Noxiustoxin and leiurutoxin III, two homologous peptide toxins with
RT   binding properties to synaptosomal membrane K+ channels.";
RL   Biochem. Int. 27:953-962(1992).
CC   -!- FUNCTION: Blocker of potassium channels.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- SIMILARITY: Belongs to the short scorpion toxin superfamily. Potassium
CC       channel inhibitor family. {ECO:0000305}.
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DR   PIR; A48389; A48389.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ion channel impairing toxin; Neurotoxin;
KW   Potassium channel impairing toxin; Secreted; Toxin.
FT   CHAIN           1..>14
FT                   /note="Leiurutoxin-3"
FT                   /id="PRO_0000066830"
FT   NON_TER         14
SQ   SEQUENCE   14 AA;  1588 MW;  83C67CCBD691205E CRC64;
     GLIDVRCYDS SQCE