SCL14_ARATH
ID SCL14_ARATH Reviewed; 769 AA.
AC Q9XE58; Q9LNX6;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Scarecrow-like protein 14;
DE Short=AtSCL14;
DE AltName: Full=GRAS family protein 2;
DE Short=AtGRAS-2;
GN Name=SCL14; OrderedLocusNames=At1g07530; ORFNames=F22G5.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX PubMed=10341448; DOI=10.1046/j.1365-313x.1999.00431.x;
RA Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.;
RT "The GRAS gene family in Arabidopsis: sequence characterization and basic
RT expression analysis of the SCARECROW-LIKE genes.";
RL Plant J. 18:111-119(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [5]
RP GENE FAMILY, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q9XE58; Q39140: TGA6; NbExp=3; IntAct=EBI-25523217, EBI-541321;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18500650}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, shoots, flowers and siliques.
CC {ECO:0000269|PubMed:10341448, ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD24412.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AAF79548.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g07520 and At1g07530.; Evidence={ECO:0000305};
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DR EMBL; AF036309; AAD24412.1; ALT_SEQ; mRNA.
DR EMBL; AC022464; AAF79548.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28139.1; -; Genomic_DNA.
DR PIR; T51232; T51232.
DR RefSeq; NP_172233.1; NM_100627.5.
DR AlphaFoldDB; Q9XE58; -.
DR SMR; Q9XE58; -.
DR BioGRID; 22508; 3.
DR IntAct; Q9XE58; 1.
DR STRING; 3702.AT1G07530.1; -.
DR iPTMnet; Q9XE58; -.
DR PaxDb; Q9XE58; -.
DR PRIDE; Q9XE58; -.
DR ProteomicsDB; 226598; -.
DR EnsemblPlants; AT1G07530.1; AT1G07530.1; AT1G07530.
DR GeneID; 837267; -.
DR Gramene; AT1G07530.1; AT1G07530.1; AT1G07530.
DR KEGG; ath:AT1G07530; -.
DR Araport; AT1G07530; -.
DR TAIR; locus:2025022; AT1G07530.
DR eggNOG; ENOG502QSQ6; Eukaryota.
DR HOGENOM; CLU_011924_2_2_1; -.
DR InParanoid; Q9XE58; -.
DR OMA; QWPALIY; -.
DR OrthoDB; 202454at2759; -.
DR PhylomeDB; Q9XE58; -.
DR PRO; PR:Q9XE58; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9XE58; baseline and differential.
DR Genevisible; Q9XE58; AT.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0080183; P:response to photooxidative stress; IMP:TAIR.
DR GO; GO:0009410; P:response to xenobiotic stimulus; IMP:TAIR.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..769
FT /note="Scarecrow-like protein 14"
FT /id="PRO_0000350856"
FT DOMAIN 384..765
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..451
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 470..536
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 552..584
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 593..687
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 690..765
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 501..505
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 279..293
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 302..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 127
FT /note="Y -> D (in Ref. 1; AAD24412)"
FT /evidence="ECO:0000305"
FT CONFLICT 145
FT /note="D -> H (in Ref. 1; AAD24412)"
FT /evidence="ECO:0000305"
FT CONFLICT 677..678
FT /note="EK -> VF (in Ref. 1; AAD24412)"
FT /evidence="ECO:0000305"
FT CONFLICT 691
FT /note="C -> S (in Ref. 1; AAD24412)"
FT /evidence="ECO:0000305"
FT CONFLICT 699..700
FT /note="RP -> SR (in Ref. 1; AAD24412)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 769 AA; 85929 MW; BA52E28E9ED655B2 CRC64;
MGSYPDGFPG SMDELDFNKD FDLPPSSNQT LGLANGFYLD DLDFSSLDPP EAYPSQNNNN
NNINNKAVAG DLLSSSSDDA DFSDSVLKYI SQVLMEEDME EKPCMFHDAL ALQAAEKSLY
EALGEKYPSS SSASSVDHPE RLASDSPDGS CSGGAFSDYA STTTTTSSDS HWSVDGLENR
PSWLHTPMPS NFVFQSTSRS NSVTGGGGGG NSAVYGSGFG DDLVSNMFKD DELAMQFKKG
VEEASKFLPK SSQLFIDVDS YIPMNSGSKE NGSEVFVKTE KKDETEHHHH HSYAPPPNRL
TGKKSHWRDE DEDFVEERSN KQSAVYVEES ELSEMFDKIL VCGPGKPVCI LNQNFPTESA
KVVTAQSNGA KIRGKKSTST SHSNDSKKET ADLRTLLVLC AQAVSVDDRR TANEMLRQIR
EHSSPLGNGS ERLAHYFANS LEARLAGTGT QIYTALSSKK TSAADMLKAY QTYMSVCPFK
KAAIIFANHS MMRFTANANT IHIIDFGISY GFQWPALIHR LSLSRPGGSP KLRITGIELP
QRGFRPAEGV QETGHRLARY CQRHNVPFEY NAIAQKWETI QVEDLKLRQG EYVVVNSLFR
FRNLLDETVL VNSPRDAVLK LIRKINPNVF IPAILSGNYN APFFVTRFRE ALFHYSAVFD
MCDSKLARED EMRLMYEKEF YGREIVNVVA CEGTERVERP ETYKQWQARL IRAGFRQLPL
EKELMQNLKL KIENGYDKNF DVDQNGNWLL QGWKGRIVYA SSLWVPSSS
