SCL1_ARATH
ID SCL1_ARATH Reviewed; 593 AA.
AC Q9SDQ3; Q9XE51;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Scarecrow-like protein 1;
DE Short=AtSCL1;
DE AltName: Full=GRAS family protein 4;
DE Short=AtGRAS-4;
GN Name=SCL1; OrderedLocusNames=At1g21450; ORFNames=F24J8.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10817761;
RA Bolle C., Koncz C., Chua N.-H.;
RT "PAT1, a new member of the GRAS family, is involved in phytochrome A signal
RT transduction.";
RL Genes Dev. 14:1269-1278(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 242-593, AND TISSUE SPECIFICITY.
RX PubMed=10341448; DOI=10.1046/j.1365-313x.1999.00431.x;
RA Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.;
RT "The GRAS gene family in Arabidopsis: sequence characterization and basic
RT expression analysis of the SCARECROW-LIKE genes.";
RL Plant J. 18:111-119(1999).
RN [7]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [8]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, shoots, leaves,
CC flowers and siliques. {ECO:0000269|PubMed:10341448,
CC ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF210731; AAF21043.1; -; mRNA.
DR EMBL; AC015447; AAF87898.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30103.1; -; Genomic_DNA.
DR EMBL; AY045833; AAK76507.1; -; mRNA.
DR EMBL; AY096626; AAM20276.1; -; mRNA.
DR EMBL; AY084492; AAM61062.1; -; mRNA.
DR EMBL; AF036300; AAD24403.1; -; mRNA.
DR PIR; E86347; E86347.
DR PIR; T51234; T51234.
DR RefSeq; NP_173566.1; NM_101996.4.
DR AlphaFoldDB; Q9SDQ3; -.
DR SMR; Q9SDQ3; -.
DR BioGRID; 23982; 3.
DR STRING; 3702.AT1G21450.1; -.
DR PaxDb; Q9SDQ3; -.
DR PRIDE; Q9SDQ3; -.
DR ProteomicsDB; 232803; -.
DR EnsemblPlants; AT1G21450.1; AT1G21450.1; AT1G21450.
DR GeneID; 838743; -.
DR Gramene; AT1G21450.1; AT1G21450.1; AT1G21450.
DR KEGG; ath:AT1G21450; -.
DR Araport; AT1G21450; -.
DR TAIR; locus:2026982; AT1G21450.
DR eggNOG; ENOG502QPVN; Eukaryota.
DR HOGENOM; CLU_011924_6_1_1; -.
DR InParanoid; Q9SDQ3; -.
DR OMA; YGPEPYN; -.
DR OrthoDB; 376686at2759; -.
DR PhylomeDB; Q9SDQ3; -.
DR PRO; PR:Q9SDQ3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SDQ3; baseline and differential.
DR Genevisible; Q9SDQ3; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR030011; Scarecrow-like_1.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 2.
DR PANTHER; PTHR31636:SF269; PTHR31636:SF269; 2.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..593
FT /note="Scarecrow-like protein 1"
FT /id="PRO_0000350846"
FT DOMAIN 213..593
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 29..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..280
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 299..364
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 380..411
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 421..515
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 518..593
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 330..334
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 29..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 66700 MW; CDDBD9A2722238A1 CRC64;
MVEQTVVREH IKARVMSLVR SAEPSSYRNP KLYTLNENGN NNGVSSAQIF DPDRSKNPCL
TDDSYPSQSY EKYFLDSPTD EFVQHPIGSG ASVSSFGSLD SFPYQSRPVL GCSMEFQLPL
DSTSTSSTRL LGDYQAVSYS PSMDVVEEFD DEQMRSKIQE LERALLGDED DKMVGIDNLM
EIDSEWSYQN ESEQHQDSPK ESSSADSNSH VSSKEVVSQA TPKQILISCA RALSEGKLEE
ALSMVNELRQ IVSIQGDPSQ RIAAYMVEGL AARMAASGKF IYRALKCKEP PSDERLAAMQ
VLFEVCPCFK FGFLAANGAI LEAIKGEEEV HIIDFDINQG NQYMTLIRSI AELPGKRPRL
RLTGIDDPES VQRSIGGLRI IGLRLEQLAE DNGVSFKFKA MPSKTSIVSP STLGCKPGET
LIVNFAFQLH HMPDESVTTV NQRDELLHMV KSLNPKLVTV VEQDVNTNTS PFFPRFIEAY
EYYSAVFESL DMTLPRESQE RMNVERQCLA RDIVNIVACE GEERIERYEA AGKWRARMMM
AGFNPKPMSA KVTNNIQNLI KQQYCNKYKL KEEMGELHFC WEEKSLIVAS AWR
