SCL21_ARATH
ID SCL21_ARATH Reviewed; 413 AA.
AC Q9S7H5; Q67ZL8; Q67ZX7;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Scarecrow-like protein 21;
DE Short=AtSCL21;
DE AltName: Full=GRAS family protein 11;
DE Short=AtGRAS-11;
GN Name=SCL21; OrderedLocusNames=At2g04890; ORFNames=F1O13.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10817761;
RA Bolle C., Koncz C., Chua N.-H.;
RT "PAT1, a new member of the GRAS family, is involved in phytochrome A signal
RT transduction.";
RL Genes Dev. 14:1269-1278(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [7]
RP INTERACTION WITH PARASITIC NEMATODE PEPTIDE 16D10.
RX PubMed=16673933; DOI=10.1094/mpmi-19-0463;
RA Huang G., Dong R., Allen R., Davis E.L., Baum T.J., Hussey R.S.;
RT "A root-knot nematode secretory peptide functions as a ligand for a plant
RT transcription factor.";
RL Mol. Plant Microbe Interact. 19:463-470(2006).
RN [8]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with Meloidogyne incognita 16D10.
CC {ECO:0000269|PubMed:16673933}.
CC -!- INTERACTION:
CC Q9S7H5; Q9LY29: ERF115; NbExp=3; IntAct=EBI-1238472, EBI-2130977;
CC Q9S7H5; Q38Q40: ERF122; NbExp=3; IntAct=EBI-1238472, EBI-25514205;
CC Q9S7H5; Q8GXL7: GATA24; NbExp=6; IntAct=EBI-1238472, EBI-4426127;
CC Q9S7H5; Q8H1G0: GATA28; NbExp=3; IntAct=EBI-1238472, EBI-4435064;
CC Q9S7H5; Q9C9L2: TCP15; NbExp=3; IntAct=EBI-1238472, EBI-4426144;
CC Q9S7H5; Q8LPR5: TCP4; NbExp=3; IntAct=EBI-1238472, EBI-15192325;
CC Q9S7H5; P43273: TGA2; NbExp=3; IntAct=EBI-1238472, EBI-541307;
CC Q9S7H5; Q8GY55: TIFY4B; NbExp=4; IntAct=EBI-1238472, EBI-15206004;
CC Q9S7H5; Q84MB2: TIFY8; NbExp=4; IntAct=EBI-1238472, EBI-4426557;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, cotyledons, leaves
CC and flowers. {ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
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DR EMBL; AF210732; AAF21044.1; -; mRNA.
DR EMBL; AC006955; AAM15339.1; -; Genomic_DNA.
DR EMBL; AC007211; AAD25580.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05882.1; -; Genomic_DNA.
DR EMBL; AK175210; BAD42973.1; -; mRNA.
DR EMBL; AK175990; BAD43753.1; -; mRNA.
DR EMBL; AK176099; BAD43862.1; -; mRNA.
DR EMBL; AK221099; BAD94984.1; -; mRNA.
DR EMBL; BT026455; ABH04562.1; -; mRNA.
DR PIR; G84462; G84462.
DR RefSeq; NP_178566.1; NM_126521.3.
DR AlphaFoldDB; Q9S7H5; -.
DR SMR; Q9S7H5; -.
DR BioGRID; 437; 47.
DR IntAct; Q9S7H5; 40.
DR STRING; 3702.AT2G04890.1; -.
DR PaxDb; Q9S7H5; -.
DR PRIDE; Q9S7H5; -.
DR ProteomicsDB; 232804; -.
DR EnsemblPlants; AT2G04890.1; AT2G04890.1; AT2G04890.
DR GeneID; 815036; -.
DR Gramene; AT2G04890.1; AT2G04890.1; AT2G04890.
DR KEGG; ath:AT2G04890; -.
DR Araport; AT2G04890; -.
DR TAIR; locus:2044973; AT2G04890.
DR eggNOG; ENOG502QRZD; Eukaryota.
DR HOGENOM; CLU_011924_0_1_1; -.
DR InParanoid; Q9S7H5; -.
DR OMA; LLMARWC; -.
DR OrthoDB; 483185at2759; -.
DR PhylomeDB; Q9S7H5; -.
DR PRO; PR:Q9S7H5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9S7H5; baseline and differential.
DR Genevisible; Q9S7H5; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..413
FT /note="Scarecrow-like protein 21"
FT /id="PRO_0000350860"
FT DOMAIN 41..413
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 48..108
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 127..192
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 201..233
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 242..336
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 339..413
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 158..162
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT CONFLICT 27
FT /note="E -> G (in Ref. 4; BAD94984/BAD43753)"
FT /evidence="ECO:0000305"
FT CONFLICT 338
FT /note="I -> M (in Ref. 4; BAD94984/BAD43753)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 413 AA; 46468 MW; 8E78B3976B0B1A5D CRC64;
MDNVRGSIML QPLPEIAESI DDAICHELSM WPDDAKDLLL IVEAISRGDL KLVLVACAKA
VSENNLLMAR WCMGELRGMV SISGEPIQRL GAYMLEGLVA RLAASGSSIY KSLQSREPES
YEFLSYVYVL HEVCPYFKFG YMSANGAIAE AMKDEERIHI IDFQIGQGSQ WIALIQAFAA
RPGGAPNIRI TGVGDGSVLV TVKKRLEKLA KKFDVPFRFN AVSRPSCEVE VENLDVRDGE
ALGVNFAYML HHLPDESVSM ENHRDRLLRM VKSLSPKVVT LVEQECNTNT SPFLPRFLET
LSYYTAMFES IDVMLPRNHK ERINIEQHCM ARDVVNIIAC EGAERIERHE LLGKWKSRFS
MAGFEPYPLS SIISATIRAL LRDYSNGYAI EERDGALYLG WMDRILVSSC AWK
