SCL28_ARATH
ID SCL28_ARATH Reviewed; 658 AA.
AC Q9CAN3;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Scarecrow-like protein 28;
DE Short=AtSCL28;
DE AltName: Full=GRAS family protein 8;
DE Short=AtGRAS-8;
GN Name=SCL28; OrderedLocusNames=At1g63100; ORFNames=F16M19.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP INTERACTION WITH CYP95.
RX PubMed=15166240; DOI=10.1074/jbc.m400270200;
RA Lorkovic Z.J., Lopato S., Pexa M., Lehner R., Barta A.;
RT "Interactions of Arabidopsis RS domain containing cyclophilins with SR
RT proteins and U1 and U11 small nuclear ribonucleoprotein-specific proteins
RT suggest their involvement in pre-mRNA Splicing.";
RL J. Biol. Chem. 279:33890-33898(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [5]
RP INTERACTION WITH SNRNP35.
RX PubMed=15987817; DOI=10.1261/rna.2440305;
RA Lorkovic Z.J., Lehner R., Forstner C., Barta A.;
RT "Evolutionary conservation of minor U12-type spliceosome between plants and
RT humans.";
RL RNA 11:1095-1107(2005).
RN [6]
RP GENE FAMILY, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with SNRNP35 and CYP95.
CC {ECO:0000269|PubMed:15166240, ECO:0000269|PubMed:15987817}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18500650}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and sepals.
CC {ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
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DR EMBL; AC010795; AAG51600.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59206.1; -; Genomic_DNA.
DR PIR; D96656; D96656.
DR RefSeq; NP_176498.1; NM_104988.2.
DR AlphaFoldDB; Q9CAN3; -.
DR SMR; Q9CAN3; -.
DR BioGRID; 27834; 7.
DR STRING; 3702.AT1G63100.1; -.
DR iPTMnet; Q9CAN3; -.
DR PaxDb; Q9CAN3; -.
DR PRIDE; Q9CAN3; -.
DR EnsemblPlants; AT1G63100.2; AT1G63100.2; AT1G63100.
DR GeneID; 842613; -.
DR Gramene; AT1G63100.2; AT1G63100.2; AT1G63100.
DR KEGG; ath:AT1G63100; -.
DR Araport; AT1G63100; -.
DR TAIR; locus:2015243; AT1G63100.
DR eggNOG; ENOG502QU5D; Eukaryota.
DR HOGENOM; CLU_016521_0_0_1; -.
DR InParanoid; Q9CAN3; -.
DR OrthoDB; 335500at2759; -.
DR PhylomeDB; Q9CAN3; -.
DR PRO; PR:Q9CAN3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9CAN3; baseline and differential.
DR Genevisible; Q9CAN3; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:1900459; P:positive regulation of brassinosteroid mediated signaling pathway; IEA:EnsemblPlants.
DR GO; GO:0007346; P:regulation of mitotic cell cycle; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 2.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..658
FT /note="Scarecrow-like protein 28"
FT /id="PRO_0000350865"
FT DOMAIN 265..654
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 43..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..336
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 355..420
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 430..462
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 471..563
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 566..654
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 386..390
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 213..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 73481 MW; 8153B76368954A6B CRC64;
MLAGCSSSSL LSPTRRLRSE AVAATSATVS AHFPMNTQRL DLPCSSSFSR KETPSSRPLG
RSISLDNSNN NNNKPIERKT KTSGCSLKQN IKLPPLATTR GNGEGFSWNN DNNNRGKSLK
RLAEEDESCL SRAKRTKCEN EGGFWFEHFT GQDSSSPALP FSLTCSGDDE EKVCFVPSEV
ISQPLPNWVD SVITELAGIG DKDVESSLPA AVKEASGGSS TSASSESRSL SHRVPEPTNG
SRNPYSHRGA TEERTTGNIN NNNNRNDLQR DFELVNLLTG CLDAIRSRNI AAINHFIART
GDLASPRGRT PMTRLIAYYI EALALRVARM WPHIFHIAPP REFDRTVEDE SGNALRFLNQ
VTPIPKFIHF TANEMLLRAF EGKERVHIID FDIKQGLQWP SFFQSLASRI NPPHHVRITG
IGESKLELNE TGDRLHGFAE AMNLQFEFHP VVDRLEDVRL WMLHVKEGES VAVNCVMQMH
KTLYDGTGAA IRDFLGLIRS TNPIALVLAE QEAEHNSEQL ETRVCNSLKY YSAMFDAIHT
NLATDSLMRV KVEEMLFGRE IRNIVACEGS HRQERHVGFR HWRRMLEQLG FRSLGVSERE
VLQSKMLLRM YGSDNEGFFN VERSDEDNGG EGGRGGGVTL RWSEQPLYTI SAWTTGGN
