SCL5_ARATH
ID SCL5_ARATH Reviewed; 597 AA.
AC Q8H125; Q7EXH0; Q94BW9; Q9LPT0; Q9XE53;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Scarecrow-like protein 5;
DE Short=AtSCL5;
DE AltName: Full=GRAS family protein 6;
DE Short=AtGRAS-6;
GN Name=SCL5; OrderedLocusNames=At1g50600; ORFNames=F11F12.8, F17J6.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 292-597, AND TISSUE SPECIFICITY.
RX PubMed=10341448; DOI=10.1046/j.1365-313x.1999.00431.x;
RA Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.;
RT "The GRAS gene family in Arabidopsis: sequence characterization and basic
RT expression analysis of the SCARECROW-LIKE genes.";
RL Plant J. 18:111-119(1999).
RN [5]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [6]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q8H125; Q9SK67: ERF120; NbExp=3; IntAct=EBI-15395779, EBI-25515179;
CC Q8H125; Q38Q40: ERF122; NbExp=3; IntAct=EBI-15395779, EBI-25514205;
CC Q8H125; Q9LQF0: TCP23; NbExp=3; IntAct=EBI-15395779, EBI-15192297;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, shoots, leaves,
CC flowers and siliques. {ECO:0000269|PubMed:10341448,
CC ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF87875.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG51190.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAK62666.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC012561; AAF87875.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC079279; AAG51190.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE32568.1; -; Genomic_DNA.
DR EMBL; AY034929; AAK59436.2; -; mRNA.
DR EMBL; AY039611; AAK62666.1; ALT_INIT; mRNA.
DR EMBL; BT000883; AAN41283.1; -; mRNA.
DR EMBL; AF036302; AAD24405.1; -; mRNA.
DR PIR; E96542; E96542.
DR PIR; T51236; T51236.
DR RefSeq; NP_001323176.1; NM_001333446.1.
DR RefSeq; NP_175475.2; NM_103942.3.
DR AlphaFoldDB; Q8H125; -.
DR SMR; Q8H125; -.
DR BioGRID; 26707; 5.
DR IntAct; Q8H125; 4.
DR STRING; 3702.AT1G50600.1; -.
DR iPTMnet; Q8H125; -.
DR PaxDb; Q8H125; -.
DR PRIDE; Q8H125; -.
DR ProteomicsDB; 232911; -.
DR EnsemblPlants; AT1G50600.1; AT1G50600.1; AT1G50600.
DR GeneID; 841482; -.
DR Gramene; AT1G50600.1; AT1G50600.1; AT1G50600.
DR KEGG; ath:AT1G50600; -.
DR Araport; AT1G50600; -.
DR TAIR; locus:2008076; AT1G50600.
DR eggNOG; ENOG502QWDB; Eukaryota.
DR HOGENOM; CLU_011924_6_0_1; -.
DR InParanoid; Q8H125; -.
DR PhylomeDB; Q8H125; -.
DR PRO; PR:Q8H125; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8H125; baseline and differential.
DR Genevisible; Q8H125; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..597
FT /note="Scarecrow-like protein 5"
FT /id="PRO_0000350849"
FT DOMAIN 218..597
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 111..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..285
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 304..369
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 385..417
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 426..520
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 523..597
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 335..339
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT CONFLICT 292..294
FT /note="CKD -> GTS (in Ref. 4; AAD24405)"
FT /evidence="ECO:0000305"
FT CONFLICT 562
FT /note="K -> E (in Ref. 3; AAK62666)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 597 AA; 66641 MW; FF04283230556502 CRC64;
MRLSVFIIPL VESRQASGII NKQSTSLLIR FSLYLEASIS TKSFFSKSQR ISQTQSPICL
SANYYQPDNL DMEATQKHMI QEGSSMFYHQ PSSVKQMDLS VQTFDSYCTL ESSSGTKSHP
CLNNKNNSSS TTSFSSNESP ISQANNNNLS RFNNHSPEEN NNSPLSGSSA TNTNETELSL
MLKDLETAMM EPDVDNSYNN QGGFGQQHGV VSSAMYRSME MISRGDLKGV LYECAKAVEN
YDLEMTDWLI SQLQQMVSVS GEPVQRLGAY MLEGLVARLA SSGSSIYKAL RCKDPTGPEL
LTYMHILYEA CPYFKFGYES ANGAIAEAVK NESFVHIIDF QISQGGQWVS LIRALGARPG
GPPNVRITGI DDPRSSFARQ GGLELVGQRL GKLAEMCGVP FEFHGAALCC TEVEIEKLGV
RNGEALAVNF PLVLHHMPDE SVTVENHRDR LLRLVKHLSP NVVTLVEQEA NTNTAPFLPR
FVETMNHYLA VFESIDVKLA RDHKERINVE QHCLAREVVN LIACEGVERE ERHEPLGKWR
SRFHMAGFKP YPLSSYVNAT IKGLLESYSE KYTLEERDGA LYLGWKNQPL ITSCAWR
