SCL6_ARATH
ID SCL6_ARATH Reviewed; 558 AA.
AC O81316; B2CV54; Q9SYQ4;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Scarecrow-like protein 6;
DE Short=AtSCL6;
DE AltName: Full=GRAS family protein 22;
DE Short=AtGRAS-22;
DE AltName: Full=SCL6-IV;
GN Name=SCL6; OrderedLocusNames=At4g00150; ORFNames=F6N15.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 140-307.
RC STRAIN=cv. Ag-0, cv. An-1, cv. Bay-0, cv. Br-0, cv. C24, cv. Ct-0,
RC cv. Cvi-0, cv. Edi-0, cv. Ei-2, cv. Ga-0, cv. Gy-0, cv. Kas-2, cv. Ll-0,
RC cv. Mrk-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Sorbo,
RC cv. Wassilewskija, cv. Wei-0, and cv. Wt-5;
RX PubMed=18305205; DOI=10.1104/pp.108.116582;
RA Ehrenreich I.M., Purugganan M.D.;
RT "Sequence variation of microRNAs and their binding sites in Arabidopsis.";
RL Plant Physiol. 146:1974-1982(2008).
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 181-558, AND TISSUE SPECIFICITY.
RX PubMed=10341448; DOI=10.1046/j.1365-313x.1999.00431.x;
RA Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.;
RT "The GRAS gene family in Arabidopsis: sequence characterization and basic
RT expression analysis of the SCARECROW-LIKE genes.";
RL Plant J. 18:111-119(1999).
RN [6]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [7]
RP INTERACTION WITH PARASITIC NEMATODE PEPTIDE 16D10.
RX PubMed=16673933; DOI=10.1094/mpmi-19-0463;
RA Huang G., Dong R., Allen R., Davis E.L., Baum T.J., Hussey R.S.;
RT "A root-knot nematode secretory peptide functions as a ligand for a plant
RT transcription factor.";
RL Mol. Plant Microbe Interact. 19:463-470(2006).
RN [8]
RP GENE FAMILY, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with Meloidogyne incognita 16D10.
CC {ECO:0000269|PubMed:16673933}.
CC -!- INTERACTION:
CC O81316; Q9SAK5: APL; NbExp=3; IntAct=EBI-4428591, EBI-4437350;
CC O81316; Q8LAJ7: PHL3; NbExp=3; IntAct=EBI-4428591, EBI-4443730;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18500650}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:10341448, ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
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DR EMBL; AF069299; AAC19296.1; -; Genomic_DNA.
DR EMBL; AL161471; CAB80773.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE81829.1; -; Genomic_DNA.
DR EMBL; AF462831; AAL58919.1; -; mRNA.
DR EMBL; AY133537; AAM91367.1; -; mRNA.
DR EMBL; AF036303; AAD24406.1; -; mRNA.
DR EMBL; EU550755; ACB31517.1; -; Genomic_DNA.
DR EMBL; EU550756; ACB31518.1; -; Genomic_DNA.
DR EMBL; EU550757; ACB31519.1; -; Genomic_DNA.
DR EMBL; EU550758; ACB31520.1; -; Genomic_DNA.
DR EMBL; EU550759; ACB31521.1; -; Genomic_DNA.
DR EMBL; EU550760; ACB31522.1; -; Genomic_DNA.
DR EMBL; EU550761; ACB31523.1; -; Genomic_DNA.
DR EMBL; EU550762; ACB31524.1; -; Genomic_DNA.
DR EMBL; EU550763; ACB31525.1; -; Genomic_DNA.
DR EMBL; EU550764; ACB31526.1; -; Genomic_DNA.
DR EMBL; EU550765; ACB31527.1; -; Genomic_DNA.
DR EMBL; EU550766; ACB31528.1; -; Genomic_DNA.
DR EMBL; EU550767; ACB31529.1; -; Genomic_DNA.
DR EMBL; EU550768; ACB31530.1; -; Genomic_DNA.
DR EMBL; EU550769; ACB31531.1; -; Genomic_DNA.
DR EMBL; EU550770; ACB31532.1; -; Genomic_DNA.
DR EMBL; EU550771; ACB31533.1; -; Genomic_DNA.
DR EMBL; EU550772; ACB31534.1; -; Genomic_DNA.
DR EMBL; EU550773; ACB31535.1; -; Genomic_DNA.
DR EMBL; EU550774; ACB31536.1; -; Genomic_DNA.
DR EMBL; EU550775; ACB31537.1; -; Genomic_DNA.
DR EMBL; EU550776; ACB31538.1; -; Genomic_DNA.
DR EMBL; EU550777; ACB31539.1; -; Genomic_DNA.
DR PIR; T01343; T01343.
DR PIR; T51237; T51237.
DR RefSeq; NP_191926.1; NM_116232.5.
DR AlphaFoldDB; O81316; -.
DR SMR; O81316; -.
DR BioGRID; 13497; 17.
DR IntAct; O81316; 18.
DR STRING; 3702.AT4G00150.1; -.
DR PaxDb; O81316; -.
DR PRIDE; O81316; -.
DR ProteomicsDB; 232912; -.
DR EnsemblPlants; AT4G00150.1; AT4G00150.1; AT4G00150.
DR GeneID; 828208; -.
DR Gramene; AT4G00150.1; AT4G00150.1; AT4G00150.
DR KEGG; ath:AT4G00150; -.
DR Araport; AT4G00150; -.
DR TAIR; locus:2126901; AT4G00150.
DR eggNOG; ENOG502QQQC; Eukaryota.
DR HOGENOM; CLU_013139_1_0_1; -.
DR InParanoid; O81316; -.
DR OMA; RHHAIPD; -.
DR OrthoDB; 420029at2759; -.
DR PhylomeDB; O81316; -.
DR PRO; PR:O81316; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O81316; baseline and differential.
DR Genevisible; O81316; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IMP:TAIR.
DR GO; GO:0051301; P:cell division; IMP:TAIR.
DR GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0048768; P:root hair cell tip growth; IMP:TAIR.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 2.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..558
FT /note="Scarecrow-like protein 6"
FT /id="PRO_0000350850"
FT DOMAIN 196..554
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 19..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..257
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 276..340
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 356..388
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 396..479
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 482..554
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 307..311
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT COMPBIAS 56..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 558 AA; 61168 MW; FA07D1A11B053910 CRC64;
MPLPFEEFQG KGISCFSSFS SSFPQPPSSP LLSHRKARGG EEEEEEVPAA EPTSVLDSLI
SPTSSSTVSS SHGGNSAVGG GGDATTDEQC GAIGLGDWEE QVPHDHEQSI LGLIMGDSTD
PSLELNSILQ TSPTFHDSDY SSPGFGVVDT GFGLDHHSVP PSHVSGLLIN QSQTHYTQNP
AAIFYGHHHH TPPPAKRLNP GPVGITEQLV KAAEVIESDT CLAQGILARL NQQLSSPVGK
PLERAAFYFK EALNNLLHNV SQTLNPYSLI FKIAAYKSFS EISPVLQFAN FTSNQALLES
FHGFHRLHII DFDIGYGGQW ASLMQELVLR DNAAPLSLKI TVFASPANHD QLELGFTQDN
LKHFASEINI SLDIQVLSLD LLGSISWPNS SEKEAVAVNI SAASFSHLPL VLRFVKHLSP
TIIVCSDRGC ERTDLPFSQQ LAHSLHSHTA LFESLDAVNA NLDAMQKIER FLIQPEIEKL
VLDRSRPIER PMMTWQAMFL QMGFSPVTHS NFTESQAECL VQRTPVRGFH VEKKHNSLLL
CWQRTELVGV SAWRCRSS
