SCL8_ARATH
ID SCL8_ARATH Reviewed; 640 AA.
AC Q9FYR7; Q8L553; Q9XE55;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Scarecrow-like protein 8;
DE Short=AtSCL8;
DE AltName: Full=GRAS family protein 30;
DE Short=AtGRAS-30;
GN Name=SCL8; OrderedLocusNames=At5g52510; ORFNames=T4M5.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 68-640, AND TISSUE SPECIFICITY.
RX PubMed=10341448; DOI=10.1046/j.1365-313x.1999.00431.x;
RA Pysh L.D., Wysocka-Diller J.W., Camilleri C., Bouchez D., Benfey P.N.;
RT "The GRAS gene family in Arabidopsis: sequence characterization and basic
RT expression analysis of the SCARECROW-LIKE genes.";
RL Plant J. 18:111-119(1999).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 215-640.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=15316287; DOI=10.1023/b:plan.0000038256.89809.57;
RA Tian C., Wan P., Sun S., Li J., Chen M.;
RT "Genome-wide analysis of the GRAS gene family in rice and Arabidopsis.";
RL Plant Mol. Biol. 54:519-532(2004).
RN [6]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=18500650; DOI=10.1007/s11103-008-9345-1;
RA Lee M.-H., Kim B., Song S.-K., Heo J.-O., Yu N.-I., Lee S.A., Kim M.,
RA Kim D.G., Sohn S.O., Lim C.E., Chang K.S., Lee M.M., Lim J.;
RT "Large-scale analysis of the GRAS gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 67:659-670(2008).
CC -!- FUNCTION: Probable transcription factor involved in plant development.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves and siliques.
CC {ECO:0000269|PubMed:10341448, ECO:0000269|PubMed:18500650}.
CC -!- SIMILARITY: Belongs to the GRAS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM20537.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AP000378; BAB10182.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96223.1; -; Genomic_DNA.
DR EMBL; AF036305; AAD24408.1; -; mRNA.
DR EMBL; AY099686; AAM20537.1; ALT_INIT; mRNA.
DR EMBL; AY128868; AAM91268.1; -; mRNA.
DR PIR; T51239; T51239.
DR RefSeq; NP_200064.3; NM_124630.5.
DR AlphaFoldDB; Q9FYR7; -.
DR SMR; Q9FYR7; -.
DR STRING; 3702.AT5G52510.1; -.
DR PaxDb; Q9FYR7; -.
DR PRIDE; Q9FYR7; -.
DR ProteomicsDB; 232913; -.
DR EnsemblPlants; AT5G52510.1; AT5G52510.1; AT5G52510.
DR GeneID; 835327; -.
DR Gramene; AT5G52510.1; AT5G52510.1; AT5G52510.
DR KEGG; ath:AT5G52510; -.
DR Araport; AT5G52510; -.
DR TAIR; locus:2184625; AT5G52510.
DR eggNOG; ENOG502QRJ6; Eukaryota.
DR HOGENOM; CLU_011924_6_1_1; -.
DR InParanoid; Q9FYR7; -.
DR OMA; NEACGHY; -.
DR OrthoDB; 548298at2759; -.
DR PhylomeDB; Q9FYR7; -.
DR PRO; PR:Q9FYR7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FYR7; baseline and differential.
DR Genevisible; Q9FYR7; AT.
DR GO; GO:0005737; C:cytoplasm; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR030013; Scarecrow-like_8.
DR InterPro; IPR005202; TF_GRAS.
DR PANTHER; PTHR31636; PTHR31636; 1.
DR PANTHER; PTHR31636:SF249; PTHR31636:SF249; 1.
DR Pfam; PF03514; GRAS; 1.
DR PROSITE; PS50985; GRAS; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..640
FT /note="Scarecrow-like protein 8"
FT /id="PRO_0000350852"
FT DOMAIN 256..640
FT /note="GRAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..317
FT /note="Leucine repeat I (LRI)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 333..408
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 428..460
FT /note="Leucine repeat II (LRII)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 470..563
FT /note="PFYRE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT REGION 566..640
FT /note="SAW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT MOTIF 368..372
FT /note="VHIID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01191"
FT CONFLICT 68..78
FT /note="RTLADFQAAQQ -> KDFSRFSSGSE (in Ref. 3; AAD24408)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 640 AA; 69150 MW; C333A4855A739F9B CRC64;
MESGFSGGGG GSDFYGGGGG RSIPGGPGTV INVGNNNPQT TYRNQIPGIF FDQIGNRVAG
GNGFSGKRTL ADFQAAQQHQ QQQQQQPFYS QAALNAFLSR SVKPRNYQNF QSPSPMIDLT
SVNDMSLFGG SGSSQRYGLP VPRSQTQQQQ SDYGLFGGIR MGIGSGINNY PTLTGVPCIE
PVQNRVHESE NMLNSLRELE KQLLDDDDES GGDDDVSVIT NSNSDWIQNL VTPNPNPNPV
LSFSPSSSSS SSSPSTASTT TSVCSRQTVM EIATAIAEGK TEIATEILAR VSQTPNLERN
SEEKLVDFMV AALRSRIASP VTELYGKEHL ISTQLLYELS PCFKLGFEAA NLAILDAADN
NDGGMMIPHV IDFDIGEGGQ YVNLLRTLST RRNGKSQSQN SPVVKITAVA NNVYGCLVDD
GGEERLKAVG DLLSQLGDRL GISVSFNVVT SLRLGDLNRE SLGCDPDETL AVNLAFKLYR
VPDESVCTEN PRDELLRRVK GLKPRVVTLV EQEMNSNTAP FLGRVSESCA CYGALLESVE
STVPSTNSDR AKVEEGIGRK LVNAVACEGI DRIERCEVFG KWRMRMSMAG FELMPLSEKI
AESMKSRGNR VHPGFTVKED NGGVCFGWMG RALTVASAWR
