ID   SCNM1_XENLA             Reviewed;         260 AA.
AC   Q3KQ71;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Sodium channel modifier 1;
GN   Name=scnm1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in alternative splicing of pre-mRNAs, possibly
CC       by contributing to the selection of non-consensus donor sites.
CC       {ECO:0000250|UniProtKB:Q8K136}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC       {ECO:0000250|UniProtKB:Q8K136}. Nucleus speckle
CC       {ECO:0000250|UniProtKB:Q8K136}.
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DR   EMBL; BC106358; AAI06359.1; -; mRNA.
DR   RefSeq; NP_001089700.1; NM_001096231.1.
DR   AlphaFoldDB; Q3KQ71; -.
DR   SMR; Q3KQ71; -.
DR   MaxQB; Q3KQ71; -.
DR   DNASU; 734762; -.
DR   GeneID; 734762; -.
DR   KEGG; xla:734762; -.
DR   CTD; 734762; -.
DR   Xenbase; XB-GENE-921398; scnm1.L.
DR   OMA; MLTVHRQ; -.
DR   OrthoDB; 1557322at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 734762; Expressed in testis and 19 other tissues.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR033570; SCNM1.
DR   InterPro; IPR031625; SCNM1_acidic.
DR   InterPro; IPR031622; Znf-SCNM1.
DR   PANTHER; PTHR32297; PTHR32297; 1.
DR   Pfam; PF15805; SCNM1_acidic; 1.
DR   Pfam; PF15803; zf-SCNM1; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..260
FT                   /note="Sodium channel modifier 1"
FT                   /id="PRO_0000259638"
FT   ZN_FING         42..74
FT                   /note="Matrin-type"
FT   REGION          143..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           4..20
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        143..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   260 AA;  29133 MW;  039DE14FDB7EA515 CRC64;
     MSFKRDGDDS SQLNVLKKRR VADLLASYIP EDEALLLKNG SYACTVCHHR PVFNTIDMLS
     VHRTGKKHLG GLQRYYGKKL EHKNEIQKRR HFDFVRAEDA GEKPPPGPAP LLVQTKRITQ
     NALLKSAPYN SCCSNKKVVA NSRNVYDPHS GPSTTTGLNV PLDTQPGPSQ PHTSLHSPPT
     GPCSSPTDEI PPNKNNSRHK KKGEEKFRKE IADPERERNM EHYLQLKSSG WIPDGTGKWV
     KDENVEFDSD EEEPPALPPS