ID   SCO22_RICTY             Reviewed;         203 AA.
AC   Q68WF1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 2.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=SCO2-like protein RT0576;
GN   OrderedLocusNames=RT0576;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- SIMILARITY: Belongs to the SCO1/2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAU04041.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017197; AAU04041.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_014419446.1; NC_006142.1.
DR   AlphaFoldDB; Q68WF1; -.
DR   SMR; Q68WF1; -.
DR   STRING; 257363.RT0576; -.
DR   EnsemblBacteria; AAU04041; AAU04041; RT0576.
DR   KEGG; rty:RT0576; -.
DR   eggNOG; COG1999; Bacteria.
DR   HOGENOM; CLU_050131_3_1_5; -.
DR   OMA; LMDVLMW; -.
DR   OrthoDB; 1994201at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd02968; SCO; 1.
DR   InterPro; IPR003782; SCO1/SenC.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR12151; PTHR12151; 1.
DR   Pfam; PF02630; SCO1-SenC; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Copper; Metal-binding.
FT   CHAIN           1..203
FT                   /note="SCO2-like protein RT0576"
FT                   /id="PRO_0000280798"
FT   DOMAIN          42..203
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   BINDING         80
FT                   /ligand="Cu cation"
FT                   /ligand_id="ChEBI:CHEBI:23378"
FT                   /evidence="ECO:0000250"
FT   BINDING         84
FT                   /ligand="Cu cation"
FT                   /ligand_id="ChEBI:CHEBI:23378"
FT                   /evidence="ECO:0000250"
FT   BINDING         170
FT                   /ligand="Cu cation"
FT                   /ligand_id="ChEBI:CHEBI:23378"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   203 AA;  23540 MW;  2E05822535359599 CRC64;
     MQSNIMKIII IVSLLIVVGT LYVLLSLSTP KKPLAGQVNI YKDNIKIGEA FELIDQNGEI
     FNSNKLRGHL SLIYFGFTSC PDICPTFLNK MTNIVEILHQ NQIDIIPIFI TIDPKRDTPE
     VLKEYIKNFH PKFICLTGNE HQIKDVTDKF KILYARVNGY DDDQNYMIDH SSFTYLIDKN
     GKYIKHFYLD ISAKEIMEFL RNE