SCP27_ARATH
ID SCP27_ARATH Reviewed; 459 AA.
AC Q9SFB5;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Serine carboxypeptidase-like 27;
DE EC=3.4.16.-;
DE Flags: Precursor;
GN Name=SCPL27; OrderedLocusNames=At3g07990; ORFNames=F17A17.33;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX PubMed=15908604; DOI=10.1104/pp.104.057950;
RA Fraser C.M., Rider L.W., Chapple C.;
RT "An expression and bioinformatics analysis of the Arabidopsis serine
RT carboxypeptidase-like gene family.";
RL Plant Physiol. 138:1136-1148(2005).
CC -!- FUNCTION: Probable carboxypeptidase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15908604}.
CC -!- SIMILARITY: Belongs to the peptidase S10 family. {ECO:0000305}.
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DR EMBL; AC013483; AAF21209.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74628.1; -; Genomic_DNA.
DR EMBL; BT015083; AAT71955.1; -; mRNA.
DR EMBL; BT015904; AAU95440.1; -; mRNA.
DR RefSeq; NP_187456.1; NM_111678.3.
DR AlphaFoldDB; Q9SFB5; -.
DR SMR; Q9SFB5; -.
DR STRING; 3702.AT3G07990.1; -.
DR ESTHER; arath-SCP27; Carboxypeptidase_S10.
DR MEROPS; S10.A23; -.
DR PaxDb; Q9SFB5; -.
DR PRIDE; Q9SFB5; -.
DR ProteomicsDB; 232704; -.
DR EnsemblPlants; AT3G07990.1; AT3G07990.1; AT3G07990.
DR GeneID; 819990; -.
DR Gramene; AT3G07990.1; AT3G07990.1; AT3G07990.
DR KEGG; ath:AT3G07990; -.
DR Araport; AT3G07990; -.
DR TAIR; locus:2077422; AT3G07990.
DR eggNOG; KOG1282; Eukaryota.
DR HOGENOM; CLU_008523_13_0_1; -.
DR InParanoid; Q9SFB5; -.
DR OMA; CTDRYAK; -.
DR OrthoDB; 625787at2759; -.
DR PhylomeDB; Q9SFB5; -.
DR PRO; PR:Q9SFB5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SFB5; baseline and differential.
DR Genevisible; Q9SFB5; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR033124; Ser_caboxypep_his_AS.
DR InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR PANTHER; PTHR11802; PTHR11802; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; SSF53474; 1.
DR PROSITE; PS00560; CARBOXYPEPT_SER_HIS; 1.
DR PROSITE; PS00131; CARBOXYPEPT_SER_SER; 1.
PE 2: Evidence at transcript level;
KW Carboxypeptidase; Disulfide bond; Glycoprotein; Hydrolase; Protease;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..459
FT /note="Serine carboxypeptidase-like 27"
FT /id="PRO_0000274642"
FT ACT_SITE 184
FT /evidence="ECO:0000250"
FT ACT_SITE 381
FT /evidence="ECO:0000250"
FT ACT_SITE 433
FT /evidence="ECO:0000250"
FT CARBOHYD 142
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 289
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 333
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 91..344
FT /evidence="ECO:0000250"
FT DISULFID 252..264
FT /evidence="ECO:0000250"
FT DISULFID 288..312
FT /evidence="ECO:0000250"
SQ SEQUENCE 459 AA; 52141 MW; 416109FFC2DC8499 CRC64;
MDYSFLLIIL LLTISTSCCA APSSYVEEQL RDRISNLPGQ PSNVDFRQYS GYVTVHEERG
RALFYWLVES PLARDPKSRP LVLWLNGGPG CSSVAYGAAE EIGPFRVGSD GKTLHSKLYA
WNKLANLLFL ESPAGVGFSY SNTTSDLYTT GDQRTAEDSY IFLVNWFERF PQYKHREFYI
VGESYAGHFV PQLSKLVHER NKGFKNPAIN LKGFMVGNAV TDDYHDYIGT FEYWWNHGLI
SDSTYHQLKT ACYSVSSQHP SMQCMVALRN AELEQGNIDP YSIFTKPCNS TVALKRFLKG
RYPWMSRAYD PCTERYSNVY FNRLDVQKAL HANVTRLSYP WKACSDIVGS YWDDSPLSML
PIYKELITAG LKIWVFSGDT DAVVPITATR YSVDALKLAT ITNWYPWYDH GKVGGWSQVY
KGLTLVTVAG AGHEVPLHRP RQAFILFRSF LESKPMPMT
