SCP38_ARATH
ID SCP38_ARATH Reviewed; 487 AA.
AC Q9ZUG3;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Serine carboxypeptidase-like 38;
DE EC=3.4.16.-;
DE Flags: Precursor;
GN Name=SCPL38; OrderedLocusNames=At2g05850; ORFNames=T6P5.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX PubMed=15908604; DOI=10.1104/pp.104.057950;
RA Fraser C.M., Rider L.W., Chapple C.;
RT "An expression and bioinformatics analysis of the Arabidopsis serine
RT carboxypeptidase-like gene family.";
RL Plant Physiol. 138:1136-1148(2005).
CC -!- FUNCTION: Probable carboxypeptidase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves, flowers and
CC siliques. {ECO:0000269|PubMed:15908604}.
CC -!- SIMILARITY: Belongs to the peptidase S10 family. {ECO:0000305}.
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DR EMBL; AC005970; AAC95162.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05981.1; -; Genomic_DNA.
DR EMBL; AY065440; AAL38881.1; -; mRNA.
DR EMBL; BT000980; AAN41380.1; -; mRNA.
DR PIR; B84472; B84472.
DR RefSeq; NP_178642.1; NM_126598.4.
DR AlphaFoldDB; Q9ZUG3; -.
DR SMR; Q9ZUG3; -.
DR STRING; 3702.AT2G05850.1; -.
DR ESTHER; arath-scp38; Carboxypeptidase_S10.
DR MEROPS; S10.A29; -.
DR PaxDb; Q9ZUG3; -.
DR PRIDE; Q9ZUG3; -.
DR ProteomicsDB; 226609; -.
DR EnsemblPlants; AT2G05850.1; AT2G05850.1; AT2G05850.
DR GeneID; 815137; -.
DR Gramene; AT2G05850.1; AT2G05850.1; AT2G05850.
DR KEGG; ath:AT2G05850; -.
DR Araport; AT2G05850; -.
DR TAIR; locus:2064737; AT2G05850.
DR eggNOG; KOG1282; Eukaryota.
DR HOGENOM; CLU_008523_13_0_1; -.
DR InParanoid; Q9ZUG3; -.
DR OMA; EANMLFF; -.
DR OrthoDB; 607679at2759; -.
DR PhylomeDB; Q9ZUG3; -.
DR PRO; PR:Q9ZUG3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUG3; baseline and differential.
DR Genevisible; Q9ZUG3; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR033124; Ser_caboxypep_his_AS.
DR PANTHER; PTHR11802; PTHR11802; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; SSF53474; 1.
DR PROSITE; PS00560; CARBOXYPEPT_SER_HIS; 1.
PE 2: Evidence at transcript level;
KW Carboxypeptidase; Disulfide bond; Glycoprotein; Hydrolase; Protease;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..487
FT /note="Serine carboxypeptidase-like 38"
FT /id="PRO_0000274653"
FT ACT_SITE 215
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10075"
FT ACT_SITE 407
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10075"
FT ACT_SITE 460
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10075"
FT CARBOHYD 233
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 317
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 357
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 423
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 449
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 119..368
FT /evidence="ECO:0000250"
FT DISULFID 280..290
FT /evidence="ECO:0000250"
FT DISULFID 315..336
FT /evidence="ECO:0000250"
SQ SEQUENCE 487 AA; 54731 MW; D85802C8B1F02469 CRC64;
MGKQQDWSVT ACIFLSLSLA SQIHCSSQTH FPSHKGGAGL SGDTSHFNSV SRENVLSLKE
KDLIEKLPGQ PSGISFRQYG GYVAVNEPAT RFLYYYFVEA IKPSKSTPLV LWFNGGPGCS
SVGFGAFEEL GPFRVHSDGK TLYRNPYSWN NEANMLFFEG PISVGFSYSS TPFDWEIFGE
QADKLTAEDN YMFLVNWLER FPEYKGRDVY ISGQSYAGHY IPQLAQIILH RNNQTFINLR
GISIGNPGLD LLIEADNENK FILSHGLVSQ KDFEEYSKVC DFANYDMDEC PKIMPKFSIE
HNKHLDVYNI YAPVCLNSTL SSEPKKCTTI MEVDPCRSNY VKAYLNSENV QEAMHANTTK
LPYEWKACNH YLNSVWIDAD KDASMVPILH DLMGEGVRVL VYSGDVDAAI PFTATMAVLK
TMNLTVVNEW RPWFTGGQLG GFTEDYERNL TYATVKGSGH SVPLDQPVHA LNLFTSFIRN
TPLPQTP
