SCP4_ARATH
ID SCP4_ARATH Reviewed; 441 AA.
AC Q9CAU4;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Serine carboxypeptidase-like 4;
DE EC=3.4.16.-;
DE Flags: Precursor;
GN Name=SCPL4; OrderedLocusNames=At1g73310; ORFNames=T18K17.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX PubMed=15908604; DOI=10.1104/pp.104.057950;
RA Fraser C.M., Rider L.W., Chapple C.;
RT "An expression and bioinformatics analysis of the Arabidopsis serine
RT carboxypeptidase-like gene family.";
RL Plant Physiol. 138:1136-1148(2005).
CC -!- FUNCTION: Probable carboxypeptidase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15908604}.
CC -!- SIMILARITY: Belongs to the peptidase S10 family. {ECO:0000305}.
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DR EMBL; AC010556; AAG52126.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35440.1; -; Genomic_DNA.
DR RefSeq; NP_177474.1; NM_105990.2.
DR AlphaFoldDB; Q9CAU4; -.
DR SMR; Q9CAU4; -.
DR ESTHER; arath-SCP4; Carboxypeptidase_S10.
DR MEROPS; S10.A06; -.
DR PaxDb; Q9CAU4; -.
DR PRIDE; Q9CAU4; -.
DR ProteomicsDB; 232706; -.
DR EnsemblPlants; AT1G73310.1; AT1G73310.1; AT1G73310.
DR GeneID; 843665; -.
DR Gramene; AT1G73310.1; AT1G73310.1; AT1G73310.
DR KEGG; ath:AT1G73310; -.
DR Araport; AT1G73310; -.
DR TAIR; locus:2197259; AT1G73310.
DR eggNOG; KOG1282; Eukaryota.
DR HOGENOM; CLU_008523_0_1_1; -.
DR InParanoid; Q9CAU4; -.
DR OMA; HAWANND; -.
DR OrthoDB; 607679at2759; -.
DR PhylomeDB; Q9CAU4; -.
DR BioCyc; ARA:AT1G73310-MON; -.
DR PRO; PR:Q9CAU4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9CAU4; baseline and differential.
DR Genevisible; Q9CAU4; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0019748; P:secondary metabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR PANTHER; PTHR11802; PTHR11802; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 2: Evidence at transcript level;
KW Carboxypeptidase; Disulfide bond; Glycoprotein; Hydrolase; Protease;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..441
FT /note="Serine carboxypeptidase-like 4"
FT /id="PRO_0000274618"
FT ACT_SITE 184
FT /evidence="ECO:0000250"
FT ACT_SITE 366
FT /evidence="ECO:0000250"
FT ACT_SITE 419
FT /evidence="ECO:0000250"
FT CARBOHYD 109
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 350
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 382
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 88..331
FT /evidence="ECO:0000250"
FT DISULFID 252..266
FT /evidence="ECO:0000250"
FT DISULFID 290..297
FT /evidence="ECO:0000250"
SQ SEQUENCE 441 AA; 50352 MW; E24ECE739EAF0406 CRC64;
MANNNVYSVL KSLLLLLHLV FLSKQHVDSA SIVKFLPGFE GPLPFELETG YIGVGEEEEV
QLFYYFIKSE RNPKEDPLLL WLTGGPGCSA ISGLLYQNGP LAMKLDVYNG TLPSLVSTTY
SWTKTSSMIF LDQPVGTGFS YSRTQLFNKP SDTGEAKRIH EFLQKWLGKH QEFSSNPFYV
GGDSYSGLVV PATVQEISKG NCQCCNRPIN LQGYVLGNPL TDCVYDCNYR VPFAHKMALI
SDELYESLKR TCRGEYVNVH PHDTECLKFV EEFNKLTNRV CERHILHSCC ETETPSCYSY
RFMLTTYWAN DETVRKALQI NKESIGEWTR CYRGIPYNHD IKSSVPYHMN NSIDGYRSLI
YSGDHDIQVP FLGTQAWIRS LNYSIIDDWR PWMIKDQIAG YTTSYVNKMT FATVTGGGHT
AEFTPKETFM MFQRWINGQP L
