SCPA_BACAA
ID SCPA_BACAA Reviewed; 247 AA.
AC C3P7J3;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Segregation and condensation protein A {ECO:0000255|HAMAP-Rule:MF_01805};
GN Name=scpA {ECO:0000255|HAMAP-Rule:MF_01805}; OrderedLocusNames=BAA_4300;
OS Bacillus anthracis (strain A0248).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=592021;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A0248;
RA Dodson R.J., Munk A.C., Bruce D., Detter C., Tapia R., Sutton G., Sims D.,
RA Brettin T.;
RT "Genome sequence of Bacillus anthracis A0248.";
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in chromosomal partition during cell division.
CC May act via the formation of a condensin-like complex containing Smc
CC and ScpB that pull DNA away from mid-cell into both cell halves.
CC {ECO:0000255|HAMAP-Rule:MF_01805}.
CC -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC Smc. The presence of the three proteins is required for the association
CC of the complex with DNA. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01805}.
CC Note=Associated with two foci at the outer edges of the nucleoid region
CC in young cells, and at four foci within both cell halves in older
CC cells. {ECO:0000255|HAMAP-Rule:MF_01805}.
CC -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000255|HAMAP-
CC Rule:MF_01805}.
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DR EMBL; CP001598; ACQ46405.1; -; Genomic_DNA.
DR RefSeq; WP_001199756.1; NC_012659.1.
DR AlphaFoldDB; C3P7J3; -.
DR SMR; C3P7J3; -.
DR GeneID; 45023947; -.
DR KEGG; bai:BAA_4300; -.
DR HOGENOM; CLU_038686_3_1_9; -.
DR OMA; YLVMAAM; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.580; -; 1.
DR HAMAP; MF_01805; ScpA; 1.
DR InterPro; IPR003768; ScpA.
DR InterPro; IPR023093; ScpA-like_C.
DR PANTHER; PTHR33969; PTHR33969; 1.
DR Pfam; PF02616; SMC_ScpA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm.
FT CHAIN 1..247
FT /note="Segregation and condensation protein A"
FT /id="PRO_1000187548"
SQ SEQUENCE 247 AA; 29347 MW; DD44441389FC860C CRC64;
MQYNFKVEAF EGPLDLLLHL IHRYEIDIYN IPVAEITEQY LSYVHTMKEL QLDVASEYLV
MAATLLQIKS KMLLPKHEED VLDNGDDFID DPRQELMERL IEYKKYKQVA TELKEREQER
AQLYTRPPID FTSLQQEEET NLPLDVTLYD MLAAFQKLMR RKKAEKPVTT RITRQEIPIE
QRMTDILKQL EIQGGRQSFY DLFVDDEREI MVVTFLAVLE LMKNQQIIIE QEHNFDEIFV
SSYTKSA